Results 151 to 160 of about 70,366 (259)

3-hydroxyisobutyryl-CoA hydrolase deficiency: a case description. [PDF]

Quant Imaging Med Surg
Jiang L, Wu M, Qin W, Qin L, Cheng G, Qin H, Wei J, Liao Z, Wei X, Yang L, Wei H, Qin X.   +11 more
europepmc   +1 more source

Nerve Growth Factor is Sufficient to Cause Multiple Osteoarthritis‐Relevant Pathologic Features in Naïve Murine Knee Joints

Arthritis &Rheumatology, EarlyView.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped because of side effects in the joints. Knowledge about the biologic effects of NGF on joint tissues is limited. Therefore, we explored the effects
Alia M. Obeidat, Michael D. Newton, Jun Li, Baofeng Hu, Shingo Ishihara, Lindsey Lammlin, Lucas M. Junginger, Easton C. Farrell, Lai Wang, Frank C. Ko, Richard J. Miller, Carla R. Scanzello, Tristan Maerz, Rachel E. Miller, Anne‐Marie Malfait   +14 more
wiley   +1 more source

Illuminating basal ganglia and beyond in Parkinson's disease

Movement Disorders, 2018
Vaillancourt, David, Lehéricy, Stéphane   +1 more
openaire   +4 more sources

Association of MRI-Visible Perivascular Spaces With Longitudinal Cognitive Decline Over a Decade. [PDF]

Neurology
Kohno K, Sun Y, LeFevre JD, Robb WH, Jackson TB, Liu D, Vyas Y, Sweely B, Pechman KR, Shashikumar N, Peterson A, Landman B, Davis LT, Hohman TJ, Jefferson AL.   +14 more
europepmc   +1 more source

From Interferon Signature to the Clinical Landscape: Type I Interferonopathies

Arthritis &Rheumatology, EarlyView.
Objective TypeI interferonopathies are heterogeneous diseases driven by dysregulated type I interferon (IFN‐I) signaling. Diagnosis is challenging due to clinical/molecular variability and the need for IFN‐I quantification. The aim of this study was to characterize the clinical, immunologic, genetic, molecular profiles of patients with suspected ...
Ismail Yaz, Seza Ozen, Hacer Neslihan Bildik, Canberk Ipsir, Dilara Unal, Saliha Esenboga, Begum Cicek, Mehmet Emin Seker, Fatima Aerts‐Kaya, Seher Sener, Mehmet Orhan Erkan, Hanife Avci, Deniz Cagdas, Ilhan Tezcan   +13 more
wiley   +1 more source

Pontocerebellar hypoplasia type 9 with a novel combination of compound heterozygous variants in AMPD2. [PDF]

Hum Genome Var
Dohi S, Hotta J, Ito K, Yamashita T, Ono C, Sakuma S, Komatsu K, Inoue K, Saitsu H, Hamazaki T, Seto T.   +10 more
europepmc   +1 more source

Increased Plasma Microbial tDR‐1 in At‐Risk Individuals Is Associated With Decreased Conversion to Clinical Rheumatoid Arthritis and Reduces an In Vitro Macrophage Type 1 Interferon Response

Arthritis &Rheumatology, EarlyView.
Objective Microbial small RNAs can regulate human genes. Higher plasma concentrations of microbial transfer RNA (tRNA)‐derived RNA‐1 (tDR‐1) were previously associated with lower rheumatoid arthritis (RA) disease activity. This study examined whether tDR‐1 concentrations differ in anticyclic citrullinated peptide‐3 positive (CCP3+) at‐risk individuals (
Anastasiia Phothisane, Tulsi K. Joishy, Carolina Ramirez‐Becerra, Qiong Wu, Jennifer Seifert, Marie L. Feser, Jill M. Norris, M. Kristen Demoruelle, LauraKay Moss, Kevin D. Deane, V. Michael Holers, Michelle J. Ormseth   +11 more
wiley   +1 more source

Low-Positive Myelin Oligodendrocyte Glycoprotein (MOG)-Immunoglobulin G (IgG) in Pediatric Demyelinating Disease: How Imaging Features Can Support a MOG Antibody-Associated Disease (MOGAD) Diagnosis. [PDF]

Cureus
Tang CL, Fok EWS.
europepmc   +1 more source

Peripheral Blood DNA Methylation Changes Precede Lymphoma Diagnosis in Primary Sjögren's Disease

Arthritis &Rheumatology, EarlyView.
Objective Primary Sjögren's disease (SjD) is a systemic autoimmune disease associated with an increased risk of lymphoma. The molecular mechanisms underlying lymphomagenesis remain poorly understood, and sensitive biomarkers for early identification of patients at high risk of developing lymphoma are lacking.
Hanna Lidberg, Cecilia Fugmann, Juliana Imgenberg‐Kreuz   +2 more
wiley   +1 more source

A novel <i>SLC20A2</i> variant associated with primary brain calcification: A case report. [PDF]

J Int Med Res
Chen L, Liu J, Wei S, He J.
europepmc   +1 more source