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Neurophysiology of basal ganglia diseases

2007
Publisher Summary This chapter discusses the neurophysiology of basal ganglia diseases. The anatomical structures of the basal ganglia are connected to each other by a network of interconnections and the functional organization is based on the connections with thalamus and cortical territories.
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Basal Ganglia Diseases

Abstract The concept of multiple memory systems is based on the foundational studies that have dissociated the roles of the basal ganglia and medial temporal lobe structures in memory. While it is increasingly appreciated that there are complex interactions between these systems, there is clear evidence for nondeclarative memory ...
Sephira G. Ryman, Kathleen L. Poston
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Basal Ganglia Disease And Depression

2004
Abstract Diseases of the basal ganglia are quintessential neuropsychiatric disorders, characterized by abnormal movements, cognitive impairment, and psychiatric symptoms and signs. Depression is common in these illnesses and may occur at presentation or during the course of the illness.
Anjan Chatterjee, Karen Marder
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Basal ganglia discharge abnormalities in Parkinson’s disease

2006
In the traditional model of the pathophysiology of parkinsonism, parkinsonian motor signs are viewed as the result of changes in discharge rates in the basal ganglia. However, not all experimental findings can be explained by rate changes alone, and changes in discharge patterns in these nuclei are increasingly emphasized as pathophysiologically ...
T, Wichmann, M R, DeLong
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ATROPHY OF BASAL GANGLIA IN PICK'S DISEASE

Archives of Neurology & Psychiatry, 1944
Although several observers in recent years have commented on the occurrence of changes in parts of the central nervous system other than the cerebral cortex in the condition of symmetric cortical atrophy first described by Pick, most workers continue to emphasize the cortical changes in their evaluation of the clinical signs and symptoms.
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Cortico–Basal Ganglia Circuit Function in Psychiatric Disease

Annual Review of Physiology, 2016
Circuit dysfunction models of psychiatric disease posit that pathological behavior results from abnormal patterns of electrical activity in specific cells and circuits in the brain. Many psychiatric disorders are associated with abnormal activity in the prefrontal cortex and in the basal ganglia, a set of subcortical nuclei implicated in cognitive and
Lisa A, Gunaydin, Anatol C, Kreitzer
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Pathophysiology of the basal ganglia in Parkinson's disease

Trends in Neurosciences, 2000
Insight into the organization of the basal ganglia in the normal, parkinsonian and L-dopa-induced dyskinesia states is critical for the development of newer and more effective therapies for Parkinson's disease. We believe that the basal ganglia can no longer be thought of as a unidirectional linear system that transfers information based solely on a ...
J A, Obeso   +6 more
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Diseases of the Basal Ganglia

1984
There are various conditions in which involuntary movements develop and in which pathological changes are present in the basal ganglia. Some of these conditions, and especially paralysis agitans, have been the subject of intense study during the past two decades.
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Biotin Thiamin Responsive Basal Ganglia Disease in Siblings

The Indian Journal of Pediatrics, 2017
Biotin Thiamine responsive Basal Ganglia Disease (BTBGD) is a rare treatable autosomal recessive metabolic disorder caused by mutations in SLC19A3 gene. It usually presents with encephalopathy and dystonia; if not treated, can progress to quadriparesis and death.
Vykuntaraju K, Gowda   +3 more
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Idiopathic Basal Ganglia Calcifications and Parkinson's Disease

The American Journal of Medicine, 2022
Xiaopeng, Guo   +3 more
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