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ATROPHY OF BASAL GANGLIA IN PICK'S DISEASE
Archives of Neurology & Psychiatry, 1944Although several observers in recent years have commented on the occurrence of changes in parts of the central nervous system other than the cerebral cortex in the condition of symmetric cortical atrophy first described by Pick, most workers continue to emphasize the cortical changes in their evaluation of the clinical signs and symptoms.
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Basal ganglia calcification: ‘Fahr’s disease’
Practical NeurologyBrain calcification is often detected incidentally, but basal ganglia calcification has a wide differential diagnosis, including genetic and acquired causes. Primary familial brain calcification (PFBC) (formerly ‘Fahr’s disease’) refers to neurological disorders characterised by bilateral, symmetrical deposition of calcium ...
Francesca Magrinelli +3 more
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Stereotactic microdialysis of the basal ganglia in Parkinson's disease
Journal of Neuroscience Methods, 2012Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an efficacious treatment in patients with advanced Parkinson's disease, yet the mechanisms of STN DBS are poorly understood. The aims of this study were to develop a useful method for studying neurotransmitter alterations during DBS and for the pharmacokinetics of L-dopa in brain tissue ...
Peter, Zsigmond +4 more
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1984
There are various conditions in which involuntary movements develop and in which pathological changes are present in the basal ganglia. Some of these conditions, and especially paralysis agitans, have been the subject of intense study during the past two decades.
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There are various conditions in which involuntary movements develop and in which pathological changes are present in the basal ganglia. Some of these conditions, and especially paralysis agitans, have been the subject of intense study during the past two decades.
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Abstract The concept of multiple memory systems is based on the foundational studies that have dissociated the roles of the basal ganglia and medial temporal lobe structures in memory. While it is increasingly appreciated that there are complex interactions between these systems, there is clear evidence for nondeclarative memory ...
Sephira G. Ryman, Kathleen L. Poston
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Sephira G. Ryman, Kathleen L. Poston
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Computational physiology of the basal ganglia in Parkinson’s disease
2010The normal activity of basal ganglia neurons is characterized by Poisson-like (random) firing patterns. Correlations between neurons of the same structure are weak or non-existent. By contrast, synchronous oscillations are commonly found in the basal ganglia of human patients and animal models of Parkinson's disease. The frequency of these oscillations
Michal, Rivlin-Etzion +3 more
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Basal Ganglia Disease And Depression
2004Abstract Diseases of the basal ganglia are quintessential neuropsychiatric disorders, characterized by abnormal movements, cognitive impairment, and psychiatric symptoms and signs. Depression is common in these illnesses and may occur at presentation or during the course of the illness.
Anjan Chatterjee, Karen Marder
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Depth perception in cerebellar and basal ganglia disease
Experimental Brain Research, 2006There is increasing evidence that the cerebellum and the basal ganglia serve not only a role in motor control but also in visual perception. Patients with Parkinson's disease (PD) as well as patients with cerebellar lesions exhibit impairments of vision that are not fully explained by ocular motor deficits. It is less clear to which extent these visual
Matthias, Maschke +4 more
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Basal ganglia discharge abnormalities in Parkinson’s disease
2006In the traditional model of the pathophysiology of parkinsonism, parkinsonian motor signs are viewed as the result of changes in discharge rates in the basal ganglia. However, not all experimental findings can be explained by rate changes alone, and changes in discharge patterns in these nuclei are increasingly emphasized as pathophysiologically ...
T, Wichmann, M R, DeLong
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Somatostatin is increased in the basal ganglia in Huntington disease
Annals of Neurology, 1983AbstractHuntington disease (HD) is an autosomal dominant hereditary disorder characterized by premature cell death, predominantly in the neostriatum. Decreased concentrations of several neurotransmitters and neuropeptides have been reported in the basal ganglia in Huntington disease.
N, Aronin +6 more
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