Results 221 to 230 of about 466,533 (289)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

Basal Metabolic Rate Versus Dietary Vitamin D and Calcium Intakes and the Association With Body Composition and Bone Health After Chronic Spinal Cord Injury. [PDF]

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Dora IE, Khalil RE, Adler RA, Gorgey AS.
europepmc   +1 more source

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Basal metabolic rate of inuit

American Journal of Human Biology, 1995
AbstractBasal metabolic rates (BMR) at the end of the winter of 1981–1982 were determined in both Inuit and subjects of European ancestry resident in Igloolik, N.W.T. (69°40'N, 81°W). Values for the Inuit sample (22 females, 14–53 years, and 30 males, 14–70 years) exceeded published body surface area norms by some 16–18%; they also exceeded the body ...
Andris, Rode, Roy J, Shephard
openaire   +2 more sources

Basal metabolic rate in pregnant adolescents

Clinical Nutrition ESPEN, 2018
In most clinical settings basal metabolic rate (BMR) is estimated by predictive equations (PE) but there is no specific algorithm for pregnant women. To this end, this study aimed to measure BMR (BMRm) in single-fetus primigravida 63 adolescent pregnant women recruited from primary health care units from a tropical municipality in Brazil. Additionally,
E O F, Sally, L A, Anjos, E G, Ramos, V M, Fonseca, B A M, Silva, V, Wahrlich   +5 more
openaire   +2 more sources

BASAL METABOLIC RATE IN OBESE CHILDREN

Pediatrics, 1949
An analysis of the results of 524 observations of the basal metabolism of 348 obese children is presented. Since only 3% of the basal metabolic rates were lower than minus 15% of the Child Research Council surface area-age standards, it is suggested that these standards can be used satisfactorily in the management of children with obesity.
H H, GORDON, A, ILIFF, H, McNAMARA, W R, BELL   +3 more
openaire   +2 more sources