Results 81 to 90 of about 75,758 (252)

Physiological and biochemical evolution of peach leaf buds during dormancy course under two contrasted temperature patterns

International Journal of Horticultural Science, 2006
Budbreak anomalies in temperate fruit trees grown under mild conditions have often been described. However, only few authors approached the physiological evolution of leaf buds all along the dormancy period according to the temperature pattern.
G. B. Leite, M. Bonhomme, G. L. Putti, G. Petel, J. L. Petri, R. Rageau   +5 more
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Microbiological Indicators for Assessing the Effects of Agricultural Practices on Soil Health: A Review

Agronomy
Agricultural practices significantly impact soil properties and ecological functions, highlighting the importance of comprehensive soil health assessments.
Mikhail V. Semenov, Alena D. Zhelezova, Natalya A. Ksenofontova, Ekaterina A. Ivanova, Dmitry A. Nikitin, Vyacheslav M. Semenov   +5 more
doaj   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Methodological peculiarities of basal respiration measurement of organogenic samples of peat soils

Lomonosov Soil Science Journal
Methodological peculiarities of basal respiration (BR) measurement have been studied on the peat soil samples from two taiga subzones. It is found that the BR values at the initial incubation time (30 minutes) significantly exceed the ‘classical’ variant (24 hours) and gradually decrease with time. It is observed for all types of samples.
Georgy V. Matyshak, Elena Al. Timofeeva, Maria Al. Chepurnova, Stanislav V. Chuvanov   +3 more
openaire   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Heightened mitochondrial respiration in CF cells is normalised by triple CFTR modulator therapy through mechanisms involving calcium

Heliyon
Background: Cystic fibrosis (CF) is associated with increased resting energy expenditure. However, the introduction of elexacaftor/tezacaftor/ivacaftor (ETI) has resulted in a paradigm shift in nutritional status for many people with CF, with increase ...
H.H. Jarosz-Griffiths, L.R. Caley, S. Lara-Reyna, S. Savic, I.J. Clifton, M.F. McDermott, D.G. Peckham   +6 more
doaj   +1 more source

Seasonal periodicity in man: I. Basal metabolism; respiration; cardio vascular condition.

Experimental Biology and Medicine, 1926
Four normal persons, two men and two women, have served as subjects for this investiagtion. On each, the following observations were made once a week throughout the year (February, 1925—February, 1926) under basal conditions between 8 and 10 a. m. The observations and their apparent course throughout the year follow:1.
F. R. Griffith, G. W. Pucher, J. D. Klein, M. E. Carmer   +3 more
openaire   +1 more source