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Base Composition and Host Adaptation of the SARS-CoV-2: Insight From the Codon Usage Perspective. [PDF]

open access: yesFront Microbiol, 2021
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been spreading rapidly all over the world and has raised grave concern globally.
Roy A   +9 more
europepmc   +2 more sources

Base composition, adaptation, and evolution of goose astroviruses: codon-based investigation. [PDF]

open access: yesPoult Sci, 2023
: Goose astroviruses (GoAstVs) are causative agents that account for fatal infection of goslings characterized by visceral urate deposition, resulting in severe economic losses in major goose-producing regions in China since 2017.
Guo F   +4 more
europepmc   +2 more sources

Variation in base composition underlies functional and evolutionary divergence in non-LTR retrotransposons. [PDF]

open access: yesMob DNA, 2020
Background Non-LTR retrotransposons often exhibit base composition that is markedly different from the nucleotide content of their host’s gene. For instance, the mammalian L1 element is AT-rich with a strong A bias on the positive strand, which results ...
Ruggiero RP, Boissinot S.
europepmc   +2 more sources

Local genic base composition impacts protein production and cellular fitness. [PDF]

open access: yesPeerJ, 2018
The maintenance of a G + C content that is higher than the mutational input to a genome provides support for the view that selection serves to increase G + C contents in bacteria.
Quandt EM, Traverse CC, Ochman H.
europepmc   +3 more sources

Leishmania (Viannia) braziliensis Inositol Phosphorylceramide: Distinctive Sphingoid Base Composition. [PDF]

open access: yesFront Microbiol, 2017
Inositol phosphorylceramide (IPC), the major sphingolipid in the genus Leishmania but not found in mammals, is considered a potentially useful target for chemotherapy against leishmaniasis.
De Castro Levatti EV   +6 more
europepmc   +2 more sources

Evolution of Genomic Base Composition: From Single Cell Microbes to Multicellular Animals. [PDF]

open access: yesComput Struct Biotechnol J, 2019
Whole genome sequencing (WGS) of thousands of microbial genomes has provided considerable insight into evolutionary mechanisms in the microbial world.
Bohlin J, Pettersson JH.
europepmc   +2 more sources

Base Composition Characteristics of Mammalian miRNAs. [PDF]

open access: yesJ Nucleic Acids, 2013
MicroRNAs (miRNAs) are short RNA sequences that repress protein synthesis by either inhibiting the translation of messenger RNA (mRNA) or increasing mRNA degradation.
Wang B.
europepmc   +2 more sources

The Conception of the General Content of the Composition, Structure and Working of the Informative Components of the Economic Knowledge Base [PDF]

open access: yesInformatică economică, 2008
Starting of the content aspect, on the systematic-informational positions, the general conceptional variant of the composition, structure and transformative relations of elements of the informative compartment of knowledge base (K.Bs.) of automatized ...
Tudor St. LEAHU
doaj   +2 more sources

A predictable conserved DNA base composition signature defines human core DNA replication origins. [PDF]

open access: yesNat Commun, 2020
In metazoan the DNA sequence elements characterizing origin specification are unknown. By generating and analysing 19 SNS-seq datasets from different human cell types, the authors reveal a class and features of Core origins of replication which can be ...
Akerman I   +15 more
europepmc   +2 more sources

Compression rates of microbial genomes are associated with genome size and base composition. [PDF]

open access: yesGenomics Inform
Background To what degree a string of symbols can be compressed reveals important details about its complexity. For instance, strings that are not compressible are random and carry a low information potential while the opposite is true for highly ...
Bohlin J, Pettersson JH.
europepmc   +2 more sources

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