On the Base Composition of Transposable Elements [PDF]
International Journal of Molecular Sciences, 2022 Transposable elements exhibit a base composition that is often different from the genomic average and from hosts’ genes. The most common compositional bias is towards Adenosine and Thymine, although this bias is not universal, and elements with drastically different base composition can coexist within the same genome.
Stéphane Boissinot +1 more
exaly +4 more sources
Base Composition and Host Adaptation of the SARS-CoV-2: Insight From the Codon Usage Perspective [PDF]
Frontiers in Microbiology, 2021 The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been spreading rapidly all over the world and has raised grave concern globally.
Ayan Roy +13 more
doaj +2 more sources
Base composition, adaptation, and evolution of goose astroviruses: codon-based investigation [PDF]
Poultry Science, 2023 : Goose astroviruses (GoAstVs) are causative agents that account for fatal infection of goslings characterized by visceral urate deposition, resulting in severe economic losses in major goose-producing regions in China since 2017.
Fucheng Guo +4 more
doaj +2 more sources
Variation in base composition underlies functional and evolutionary divergence in non-LTR retrotransposons [PDF]
Mobile DNA, 2020 Background Non-LTR retrotransposons often exhibit base composition that is markedly different from the nucleotide content of their host’s gene. For instance, the mammalian L1 element is AT-rich with a strong A bias on the positive strand, which results ...
Robert P. Ruggiero, Stéphane Boissinot
doaj +2 more sources
Leishmania (Viannia) braziliensis Inositol Phosphorylceramide: Distinctive Sphingoid Base Composition [PDF]
Frontiers in Microbiology, 2017 Inositol phosphorylceramide (IPC), the major sphingolipid in the genus Leishmania but not found in mammals, is considered a potentially useful target for chemotherapy against leishmaniasis.
Erica V. De Castro Levatti +7 more
doaj +2 more sources
Local genic base composition impacts protein production and cellular fitness [PDF]
PeerJ, 2018 The maintenance of a G + C content that is higher than the mutational input to a genome provides support for the view that selection serves to increase G + C contents in bacteria.
Erik M. Quandt +2 more
doaj +3 more sources
Base Composition Characteristics of Mammalian miRNAs [PDF]
Journal of Nucleic Acids, 2013 MicroRNAs (miRNAs) are short RNA sequences that repress protein synthesis by either inhibiting the translation of messenger RNA (mRNA) or increasing mRNA degradation.
Bin Wang
doaj +2 more sources
Evolution of Genomic Base Composition: From Single Cell Microbes to Multicellular Animals [PDF]
Computational and Structural Biotechnology Journal, 2019 Whole genome sequencing (WGS) of thousands of microbial genomes has provided considerable insight into evolutionary mechanisms in the microbial world.
Jon Bohlin, John H.-O. Pettersson
doaj +2 more sources
A predictable conserved DNA base composition signature defines human core DNA replication origins [PDF]
Nature Communications, 2020 In metazoan the DNA sequence elements characterizing origin specification are unknown. By generating and analysing 19 SNS-seq datasets from different human cell types, the authors reveal a class and features of Core origins of replication which can be ...
Ildem Akerman +15 more
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Compression rates of microbial genomes are associated with genome size and base composition [PDF]
Genomics & InformaticsBackground To what degree a string of symbols can be compressed reveals important details about its complexity. For instance, strings that are not compressible are random and carry a low information potential while the opposite is true for highly ...
Jon Bohlin, John H.-O. Pettersson
doaj +2 more sources