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In
Background Synonymous codon usage bias has typically been correlated with, and attributed to translational efficiency. However, there are other pressures on genomic sequence composition that can affect codon usage patterns such as mutational biases. This
O'Connell Mary J +6 more
doaj +5 more sources
CBDB: The codon bias database [PDF]
Background In many genomes, a clear preference in the usage of particular codons exists. The mechanisms that induce codon biases remain an open question; studies have attributed codon usage to translational selection, mutational bias and drift ...
Hilterbrand Adam +2 more
doaj +4 more sources
Analysis of codon usage and nucleotide composition bias in polioviruses [PDF]
Background Poliovirus, the causative agent of poliomyelitis, is a human enterovirus and a member of the family of Picornaviridae and among the most rapidly evolving viruses known.
Gu Yuan-xing +8 more
doaj +3 more sources
Sum rules of codon usage probabilities [PDF]
In the crystal basis model of the genetic code, it is deduced that the sum of usage probabilities of the codons with C and A in the third position for the quartets and/or sextets is independent of the biological species for vertebrates. A comparison with
A Sciarrino +21 more
core +5 more sources
SARS-CoV-2 Codon Usage Bias Downregulates Host Expressed Genes With Similar Codon Usage [PDF]
Severe acute respiratory syndrome has spread quickly throughout the world and was declared a pandemic by the World Health Organization (WHO). The pathogenic agent is a new coronavirus (SARS-CoV-2) that infects pulmonary cells with great effectiveness. In
Andres Mariano Alonso +3 more
doaj +5 more sources
Codon usage of human DNA viruses and its similarity to certain host genes [PDF]
Codon usages of DNA viruses had previously been shown to associate with their genome size. Codon usage of various human DNA viruses was compared to those of human genes to further understand viral codon usage and its roles in viral-host interaction ...
Thanyaporn Sirihongthong +4 more
doaj +2 more sources
Viral codon usage and the virus-host interactions [PDF]
Codon usage pattern is a specific characteristic of each species as a result of evolution and interaction between genome composition and translational machinery.
Thanyaporn Sirihongthong +3 more
doaj +2 more sources
Nuclear effects play an important role in determining codon usage-dependent human gene expression [PDF]
Codon usage biases play a significant role in determining gene expression levels. Codon usage was thought to primarily influence translation-dependent processes.
Renu Garg +4 more
doaj +2 more sources
Codon usage bias is the preferential or non-random use of synonymous codons, a ubiquitous phenomenon observed in bacteria, plants and animals. Different species have consistent and characteristic codon biases. Codon bias varies not only with species, family or group within kingdom, but also between the genes within an organism.
Sujatha Thankeswaran Parvathy +2 more
openaire +2 more sources
Strategies and Patterns of Codon Bias in Molluscum Contagiosum Virus
Trends associated with codon usage in molluscum contagiosum virus (MCV) and factors governing the evolution of codon usage have not been investigated so far.
Rahul Raveendran Nair +4 more
doaj +1 more source

