Results 11 to 20 of about 95,149 (294)

Enterovirus A Shows Unique Patterns of Codon Usage Bias in Conventional Versus Unconventional Clade

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Enterovirus A (EV-A) species cause hand, foot and mouth disease (HFMD), threatening the health of young children. Understanding the mutual codon usage pattern of the virus and its host(s) has fundamental and applied values.
Liyan Zeng   +7 more
doaj   +1 more source

Distinct signatures of codon and codon pair usage in 32 primary tumor types in the novel database CancerCoCoPUTs for cancer-specific codon usage

open access: yesGenome Medicine, 2021
Background Gene expression is highly variable across tissues of multi-cellular organisms, influencing the codon usage of the tissue-specific transcriptome.
Douglas Meyer   +10 more
doaj   +1 more source

Codon Usage Bias in Phytoplankton [PDF]

open access: yesJournal of Marine Science and Engineering, 2022
Non-random usage of synonymous codons, known as “codon bias”, has been described in many organisms, from bacteria to Drosophila, but little is known about it in phytoplankton. This phenomenon is thought to be driven by selection for translational efficiency.
Krasovec, Marc, Filatov, Dmitry
openaire   +4 more sources

Distinct responses to rare codons in select Drosophila tissues

open access: yeseLife, 2022
Codon usage bias has long been appreciated to influence protein production. Yet, relatively few studies have analyzed the impacts of codon usage on tissue-specific mRNA and protein expression.
Scott R Allen   +8 more
doaj   +1 more source

Codon usage similarity between viral and some host genes suggests a codon-specific translational regulation

open access: yesHeliyon, 2020
The codon usage pattern is a specific characteristic of each species; however, the codon usage of all of the genes in a genome is not uniform. Intriguingly, most viruses have codon usage patterns that are vastly different from the optimal codon usage of ...
Kunlakanya Jitobaom   +6 more
doaj   +1 more source

Comparative analysis of codon usage patterns of FUT2 from different species

open access: yesKuwait Journal of Science, 2022
Enterotoxigenic E. coli is an important zoonotic pathogen causing diarrhea in human and newborn animals. α - (1,2) fucosyltransferase 2 (FUT2) is closely associated with the formation of pathogenic receptors of Enterotoxigenic E. coli.
Chao Xu   +3 more
doaj   +1 more source

Codon Bias Patterns of $E.coli$'s Interacting Proteins [PDF]

open access: yes, 2015
Synonymous codons, i.e., DNA nucleotide triplets coding for the same amino acid, are used differently across the variety of living organisms. The biological meaning of this phenomenon, known as codon usage bias, is still controversial.
Cimini, Giulio   +4 more
core   +7 more sources

Modal Codon Usage: Assessing the Typical Codon Usage of a Genome [PDF]

open access: yesMolecular Biology and Evolution, 2009
Most genomes are heterogeneous in codon usage, so a codon usage study should start by defining the codon usage that is typical to the genome. Although this is commonly taken to be the genomewide average, we propose that the mode-the codon usage that matches the most genes-provides a more useful approximation of the typical codon usage of a genome.
Davis, James J., Olsen, Gary J.
openaire   +2 more sources

COUSIN (COdon Usage Similarity INdex): A normalized measure of Codon Usage Preferences [PDF]

open access: yesGenome Biology and Evolution, 2019
AbstractCodon Usage Preferences (CUPrefs) describe the unequal usage of synonymous codons at the gene, genomic region or genome scale. Numerous indices have been developed to measure the CUPrefs of a sequence. We introduce a normalized index to calculate CUPrefs called COUSIN for COdon Usage Similarity INdex.
Bourret, Jérôme   +2 more
openaire   +3 more sources

Decoding the codon usage patterns in Y-domain region of hepatitis E viruses

open access: yesJournal of Genetic Engineering and Biotechnology, 2022
Background Hepatitis E virus (HEV) is a positive-sense RNA virus belonging to the family Hepeviridae. The genome of HEV is organized into three open-reading frames (ORFs): ORF1, ORF2, and ORF3.
Zoya Shafat   +3 more
doaj   +1 more source

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