Results 1 to 10 of about 494,112 (301)

Identification of a novel HLA-G allele, HLA-G*01:66, using PolyseqOne and oxford nanopore sequencing

open access: yesFrontiers in Genetics
HLA-G*01:66 differs from HLA-G*01:01:22:01 by one missense nucleotide substitution at position 508 in exon 3.
Ran Li, Liyan Sun, Siqi Cai
doaj   +1 more source

First Draft Genome Assembly of the Malaysian Stingless Bee, Heterotrigona itama (Apidae, Meliponinae)

open access: yesData, 2020
The Malaysian stingless bee industry is hugely dependent on wild colonies. Nevertheless, the availability of new queens to establish new colonies is insufficient to meet the growing demand for hives in the industry.
Chien-Yeong Wee   +5 more
doaj   +1 more source

An extreme codon preference strategy: codon reassignment. [PDF]

open access: yesMolecular Biology and Evolution, 1991
We argue that in animal mitochondria codon reassignments, such as those for AGA and AGG from arginine to serine or of AUA from isoleucine to methionine, are the result of an interplay between biased mutational forces and selective ones. In particular, there is a marked tendency for animal mitochondria to have very small genomes and to minimize their ...
G E, Andersson, C G, Kurland
openaire   +2 more sources

A new and updated resource for codon usage tables

open access: yesBMC Bioinformatics, 2017
Due to the degeneracy of the genetic code, most amino acids can be encoded by multiple synonymous codons. Synonymous codons naturally occur with different frequencies in different organisms.
John C. Athey   +7 more
semanticscholar   +1 more source

Enterovirus A Shows Unique Patterns of Codon Usage Bias in Conventional Versus Unconventional Clade

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Enterovirus A (EV-A) species cause hand, foot and mouth disease (HFMD), threatening the health of young children. Understanding the mutual codon usage pattern of the virus and its host(s) has fundamental and applied values.
Liyan Zeng   +7 more
doaj   +1 more source

Expanding codon size

open access: yeseLife, 2022
Engineering transfer RNAs to read codons consisting of four bases requires changes in tRNA that go beyond the anticodon sequence.
Tarana Siddika   +2 more
openaire   +3 more sources

Codon Bias as a Means to Fine-Tune Gene Expression

open access: yesMolecules and Cells, 2015
The redundancy of the genetic code implies that most amino acids are encoded by multiple synonymous codons. In all domains of life, a biased frequency of synonymous codons is observed at the genome level, in functionally related genes (e.g., in operons),
Tessa E. F. Quax   +3 more
semanticscholar   +1 more source

Cloning and analysis of genome of transmissible gastroenteritis virus SC-Y strain

open access: yes浙江大学学报. 农业与生命科学版, 2007
Sixteen pair of primers covering the whole genome of TGEV were devised according to the published sequences, 16 cDNA fragments were amplified by RT-PCR. The amplified fragments were further cloned and sequenced. The genome of SC-Y strain was assembled by
SONG Zhen-hui, GUO Wan-zhu, YIN Hua-ping
doaj   +1 more source

JCat: a novel tool to adapt codon usage of a target gene to its potential expression host

open access: yesNucleic Acids Res., 2005
A novel method for the adaptation of target gene codon usage to most sequenced prokaryotes and selected eukaryotic gene expression hosts was developed to improve heterologous protein production.
A. Grote   +6 more
semanticscholar   +1 more source

Codon influence on protein expression in E. coli correlates with mRNA levels

open access: yesNature, 2016
Degeneracy in the genetic code, which enables a single protein to be encoded by a multitude of synonymous gene sequences, has an important role in regulating protein expression, but substantial uncertainty exists concerning the details of this phenomenon.
Grégory Boël   +13 more
semanticscholar   +1 more source

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