Codon-optimized genes for Y. lipolytica used in this study.
, 2023 Codon-optimized genes for Y. lipolytica used in this study.
Xiaoxi Zhu (540144) +15 more
core +1 more source
Exploring Differentially Expressed Genes and Immune Modulation in Diffuse Large B-Cell Lymphoma through RNA Sequencing Analysis [PDF]
Iranian Journal of Medical SciencesBackground: Diffuse large B-cell lymphoma (DLBCL) is globally recognized as the most prevalent and aggressive subtype of non-Hodgkin lymphoma. While conventional treatments are effective initially, the disease can become resistant or relapse over time ...
Nor Adzimah Johdi +4 more
doaj +1 more source
Frontiers in Genetics, 2020 Bacterial oxidative stress responses are generally controlled by transcription factors that modulate the synthesis of RNAs with the aid of some sRNAs that control the stability, and in some cases the translation, of specific mRNAs.
Lorenzo Eugenio Leiva +15 more
doaj +1 more source
Evolution: are the monkeys’ typewriters rigged? [PDF]
Royal Society Open Science, 2014 Evolution is presumed to proceed by random mutations, which increase an individual’s fitness. Increased fitness produces a higher survival rate for those individuals within populations and drives the variants to fixation over large timescales to produce ...
Michael R. Garvin, Anthony J. Gharrett
doaj +1 more source
RNA virus attenuation by codon pair deoptimisation is an artefact of increases in CpG/UpA dinucleotide frequencies [PDF]
, 2014 Mutating RNA virus genomes to alter codon pair (CP) frequencies and reduce translation efficiency has been advocated as a method to generate safe, attenuated virus vaccines.
David J Evans +15 more
core +1 more source
A modular and optimized single marker system for generating Trypanosoma brucei cell lines expressing T7 RNA polymerase and the tetracycline repressor [PDF]
Open Biology, 2012 Here, we present a simple modular extendable vector system for introducing the T7 RNA polymerase and tetracycline repressor genes into Trypanosoma brucei.
S. K. Poon +4 more
doaj +1 more source
Trinucleotide Repeat (TNR) expansions mining algorithm based on the Apriori algorithm
Journal of Biological ResearchThe Apriori algorithm is a data mining algorithm used exclusively for identifying associations between itemsets in a series of business transactions. In this paper, we modify this algorithm to identify associations between trinucleotide repeat expansions
Omar Alaqeeli
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Solid Phase Assembly of Fully Protected Trinucleotide Building Blocks for Codon-Based Gene Synthesis
Applied Sciences, 2019 The use of pre-formed trinucleotides, representing codons of the 20 canonical amino acids, for oligonucleotide-directed mutagenesis offers the advantage of controlled randomization and generation of “smart libraries”. We here present a method
Ruth Suchsland +3 more
doaj +1 more source
Evidence for a pathogenic role of different mutations at codon 188 of PRNP [PDF]
, 2008 Clinical and pathological changes in familial Creutzfeldt-Jakob disease (CJD) cases may be similar or indistinguishable from sporadic CJD. Therefore determination of novel mutations in PRNP remains of major importance.
Eva-Maria Grasbon-Frodl +49 more
core +2 more sources
Developing and evaluating a pollination systems knowledge assessment in a multidisciplinary course
International Journal of STEM Education, 2022 Background Although pollinators play an integral role in human well-being, their continued global decline reflects the need to provide and evaluate general pollinator knowledge to promote their conservation.
P. Citlally Jimenez +3 more
doaj +1 more source