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In 1985, we reported that a bacterium, Mycoplasma capricolum, used a deviant genetic code, namely UGA, a "universal" stop codon, was read as tryptophan. This finding, together with the deviant nuclear genetic codes in not a few organisms and a number of mitochondria, shows that the genetic code is not universal, and is in a state of evolution.
OHAMA, Takeshi +3 more
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We have previously proposed that tRNAGly was the first tRNA and glycine was the first amino acid incorporated into the genetic code. The next two amino acids incorporated would have been the other two small hydrophilic amino acids serine and aspartic ...
Harold S. Bernhardt
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Overview of tRNA Modifications in Chloroplasts
The chloroplast is a promising platform for biotechnological innovation due to its compact translation machinery. Nucleotide modifications within a minimal set of tRNAs modulate codon–anticodon interactions that are crucial for translation efficiency ...
Maxime Fages-Lartaud +1 more
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Analysis of amino acids network based on transition and transversion mutation of codons [PDF]
In this paper, we have developed a network of 20 amino acids based on a distance matrix of amino acids. This distance matrix is obtained by considering the transition and transversion mutation of codons.
Tazid Ali, Chandra Borah
doaj
Algebraic structures and distance based analysis of genetic code [PDF]
This paper explores the genetic code's algebraic structures associated with the four mRNA (or DNA) bases A, G, C, and U. We have obtained quotient group structures of codons by considering the transition and substitution mutation. In these quotient group
Chandra Borah, Tazid Ali
doaj
Detection of meta - and ortho -cleavage dioxygenases in bacterial phenol-degraders
In the last five years, in our lab, several bacterial genera capable of degrading phenol as sole carbon source were isolated from different Egyptian ecosystems. Phenol mineralization using these isolates was ranged from 55% to 0.4%.
Sahar Zaki
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On the origin of the genetic code
Mechanisms underlying how the genetic code was generated by Darwinian selection have remained elusive since the code was cracked in 1965. Here, I propose a hypothesis on the emergence of the genetic code and predict that its emergence was driven by sequential distinct selective pressures.
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Centrality based analysis of amino acids network [PDF]
A network is a crucial asset in biology for capturing and exploring interaction data in biological systems of many types, such as protein-protein communications, amino acid associations, gene regulation, and cellular metabolism.
Chandra Borah, Tazid Ali
doaj
The functional readthrough extension of malate dehydrogenase reveals a modification of the genetic code [PDF]
Translational readthrough gives rise to C-terminally extended proteins, thereby providing the cell with new protein isoforms. These may have different properties from the parental proteins if the extensions contain functional domains.
Julia Hofhuis +6 more
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Bioinformatic Analysis Reveals Archaeal tRNATyr and tRNATrp Identities in Bacteria
The tRNA identity elements for some amino acids are distinct between the bacterial and archaeal domains. Searching in recent genomic and metagenomic sequence data, we found some candidate phyla radiation (CPR) bacteria with archaeal tRNA identity for Tyr-
Takahito Mukai +3 more
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