Results 31 to 40 of about 2,389 (119)

Refactoring the Genetic Code for Increased Evolvability

open access: yesmBio, 2017
The standard genetic code is robust to mutations during transcription and translation. Point mutations are likely to be synonymous or to preserve the chemical properties of the original amino acid.
Gur Pines   +3 more
doaj   +1 more source

Clues to tRNA Evolution from the Distribution of Class II tRNAs and Serine Codons in the Genetic Code

open access: yesLife, 2016
We have previously proposed that tRNAGly was the first tRNA and glycine was the first amino acid incorporated into the genetic code. The next two amino acids incorporated would have been the other two small hydrophilic amino acids serine and aspartic ...
Harold S. Bernhardt
doaj   +1 more source

Overview of tRNA Modifications in Chloroplasts

open access: yesMicroorganisms, 2022
The chloroplast is a promising platform for biotechnological innovation due to its compact translation machinery. Nucleotide modifications within a minimal set of tRNAs modulate codon–anticodon interactions that are crucial for translation efficiency ...
Maxime Fages-Lartaud   +1 more
doaj   +1 more source

Analysis of amino acids network based on transition and transversion mutation of codons [PDF]

open access: yesNetwork Biology, 2021
In this paper, we have developed a network of 20 amino acids based on a distance matrix of amino acids. This distance matrix is obtained by considering the transition and transversion mutation of codons.
Tazid Ali, Chandra Borah
doaj  

Algebraic structures and distance based analysis of genetic code [PDF]

open access: yesNetwork Biology, 2023
This paper explores the genetic code's algebraic structures associated with the four mRNA (or DNA) bases A, G, C, and U. We have obtained quotient group structures of codons by considering the transition and substitution mutation. In these quotient group
Chandra Borah, Tazid Ali
doaj  

Detection of meta - and ortho -cleavage dioxygenases in bacterial phenol-degraders

open access: yesJournal of Applied Sciences and Environmental Management, 2006
In the last five years, in our lab, several bacterial genera capable of degrading phenol as sole carbon source were isolated from different Egyptian ecosystems. Phenol mineralization using these isolates was ranged from 55% to 0.4%.
Sahar Zaki
doaj   +1 more source

Experimental verification of the error minimization theory using non-standard genetic codes constructed in vitro

open access: yeseLife
All living systems use an almost identical standard genetic code (SGC), in which 20 amino acids are assigned non-randomly. According to the error minimization theory, amino acids are arranged to minimize the mutational effect on protein function, while ...
Ryota Miyachi, Norikazu Ichihashi
doaj   +1 more source

Centrality based analysis of amino acids network [PDF]

open access: yesNetwork Biology
A network is a crucial asset in biology for capturing and exploring interaction data in biological systems of many types, such as protein-protein communications, amino acid associations, gene regulation, and cellular metabolism.
Chandra Borah, Tazid Ali
doaj  

Evolving genetic code

open access: yesProceedings of the Japan Academy, Series B, 2008
In 1985, we reported that a bacterium, Mycoplasma capricolum, used a deviant genetic code, namely UGA, a "universal" stop codon, was read as tryptophan. This finding, together with the deviant nuclear genetic codes in not a few organisms and a number of mitochondria, shows that the genetic code is not universal, and is in a state of evolution.
OHAMA, Takeshi   +3 more
openaire   +3 more sources

The functional readthrough extension of malate dehydrogenase reveals a modification of the genetic code [PDF]

open access: yesOpen Biology, 2016
Translational readthrough gives rise to C-terminally extended proteins, thereby providing the cell with new protein isoforms. These may have different properties from the parental proteins if the extensions contain functional domains.
Julia Hofhuis   +6 more
doaj   +1 more source

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