Results 21 to 30 of about 434,115 (269)
Reprogramming the Genetic Code [PDF]
Science, 2011 Incorporating unnatural amino acids into proteins presents challenges in expanding the genetic code.
openaire +2 more sources
eLife, 2018 Organisms possessing genetic codes with unassigned codons raise the question of how cellular machinery resolves such codons and how this could impact horizontal gene transfer.
Natalie Jing Ma +4 more
doaj +1 more source
Analysis of codon usage pattern in Lonicera × heckrottii ‘Gold Flame’ based on chloroplast genome
Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 2022 Codon usage bias (CUB) was a unique feature of the genome, and revealing chloroplast genome codon usage bias can provide useful information for the evolution of plant species.
Jiaqiang ZHANG +3 more
doaj +1 more source
Mistranslation of the genetic code [PDF]
FEBS Letters, 2014 During mRNA decoding at the ribosome, deviations from stringent codon identity, or “mistranslation,” are generally deleterious and infrequent. Observations of organisms that decode some codons ambiguously, and the discovery of a compensatory increase in mistranslation frequency to combat environmental stress have changed the way we view “errors” in ...
Moghal, Adil +2 more
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Smart port city of Odessa: brilliant embodiment of Vitruvius` theories of beauty
Vitruvio: International Journal of Architectural Technology and Sustainability, 2016 The condition of successivedevelopment, sustainability of the whole is a continuous relation between the present, the past and the future. An interdisciplinary approach aimed to create the holistic picture of the world helps to get an objective ...
Andrey Dobrolubsky +2 more
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Origins and Early Evolution of the tRNA Molecule
Life, 2015 Modern transfer RNAs (tRNAs) are composed of ~76 nucleotides and play an important role as “adaptor” molecules that mediate the translation of information from messenger RNAs (mRNAs). Many studies suggest that the contemporary full-length tRNA was formed
Koji Tamura
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld +5 more
wiley +1 more source
Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine +17 more
wiley +1 more source
Gaussian-Distributed Codon Frequencies of Genomes
G3: Genes, Genomes, Genetics, 2019 DNA encodes protein primary structure using 64 different codons to specify 20 different amino acids and a stop signal. Frequencies of codon occurrence when ordered in descending sequence provide a global characterization of a genome’s preference (bias ...
Bohdan B. Khomtchouk, Wolfgang Nonner
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Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids
Pediatric Blood &Cancer, EarlyView.ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz +12 more
wiley +1 more source