Results 21 to 30 of about 1,008,463 (277)

11th IUBMB Focused Meeting on the Aminoacyl-tRNA Synthetases: Sailing a New Sea of Complex Functions in Human Biology and Disease

open access: yesBiomolecules, 2018
The 11th IUBMB Focused Meeting on Aminoacyl-tRNA Synthetases was held in Clearwater Beach, Florida from 29 October–2 November 2017, with the aim of presenting the latest research on these enzymes and promoting interchange among aminoacyl-tRNA ...
Christopher Francklyn   +2 more
doaj   +1 more source

The genetic code [PDF]

open access: yesProceedings of the National Academy of Sciences, 2014
An excerpt from the pages of Marshall Nirenberg’s laboratory notebook from 1965. See Fig. S1 for complete image. Image courtesy of the National Library of Medicine.
openaire   +2 more sources

RNA-Dependent Cysteine Biosynthesis in Bacteria and Archaea

open access: yesmBio, 2017
The diversity of the genetic code systems used by microbes on earth is yet to be elucidated. It is known that certain methanogenic archaea employ an alternative system for cysteine (Cys) biosynthesis and encoding; tRNACys is first acylated with ...
Takahito Mukai   +5 more
doaj   +1 more source

Evolving genetic code

open access: yesProceedings of the Japan Academy, Series B, 2008
In 1985, we reported that a bacterium, Mycoplasma capricolum, used a deviant genetic code, namely UGA, a "universal" stop codon, was read as tryptophan. This finding, together with the deviant nuclear genetic codes in not a few organisms and a number of mitochondria, shows that the genetic code is not universal, and is in a state of evolution.
OHAMA, Takeshi   +3 more
openaire   +3 more sources

The new (liberal) eugenics [PDF]

open access: yes, 2013
Despite the Nazi horrors, in 1953 the new eugenics was founded, when Watson and Crick postulated the double helix of DNA as the basis of chemical heredity.
Jeremy Gibbons, Nicolas Wu, Ralf Hinze
core   +1 more source

Reprogramming the Genetic Code [PDF]

open access: yesScience, 2011
Incorporating unnatural amino acids into proteins presents challenges in expanding the genetic code.
openaire   +2 more sources

A discriminator code–based DTD surveillance ensures faithful glycine delivery for protein biosynthesis in bacteria

open access: yeseLife, 2018
D-aminoacyl-tRNA deacylase (DTD) acts on achiral glycine, in addition to D-amino acids, attached to tRNA. We have recently shown that this activity enables DTD to clear non-cognate Gly-tRNAAla with 1000-fold higher efficiency than its activity on Gly ...
Santosh Kumar Kuncha   +7 more
doaj   +1 more source

Analysis of codon usage pattern in Lonicera × heckrottii ‘Gold Flame’ based on chloroplast genome

open access: yesNotulae Botanicae Horti Agrobotanici Cluj-Napoca, 2022
Codon usage bias (CUB) was a unique feature of the genome, and revealing chloroplast genome codon usage bias can provide useful information for the evolution of plant species.
Jiaqiang ZHANG   +3 more
doaj   +1 more source

Genetic code 1990. Outlook [PDF]

open access: yesExperientia, 1990
The genetic code is evolving as shown by 9 departures from the universal code: 6 of them are in mitochondria and 3 are in nuclear codes. We propose that these changes are preceded by disappearance of a codon from coding sequences in mRNA of an organism or organelle. The function of the codon that disappears is taken by other, synonymous codons, so that
openaire   +2 more sources

Organisms with alternative genetic codes resolve unassigned codons via mistranslation and ribosomal rescue

open access: yeseLife, 2018
Organisms possessing genetic codes with unassigned codons raise the question of how cellular machinery resolves such codons and how this could impact horizontal gene transfer.
Natalie Jing Ma   +4 more
doaj   +1 more source

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