Results 41 to 50 of about 445,931 (266)
Translation elongation can control translation initiation on eukaryotic mRNAs [PDF]
, 2013 Synonymous codons encode the same amino acid, but differ in other biophysical properties. The evolutionary selection of codons whose properties are optimal for a cell generates the phenomenon of codon bias.
Kazana, Eleanna +5 more
core +1 more source
Acta Limnologica Brasiliensia, 2020 : Aim Structural changes in phytoplankton was evaluated in one ultraoligotrophic and two oligotrophic cascading reservoirs during two climatic periods (austral winter and summer) of 2014. Changes in phytoplankton biomass, species composition, and codons
Ana Margarita Loaiza-Restano +3 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Codon-Restrained Method for Both Eliminating and Creating Intragenic Bacterial Promoters
, 2022 Future applications of synthetic biology will require refactored genetic sequences devoid of internal regulatory elements within coding sequences. These regulatory elements include cryptic and intragenic promoters, which may constitute up to a third of ...
Paul R. Jaschke (3096486) +5 more
core +2 more sources
Strategies and Patterns of Codon Bias in Molluscum Contagiosum Virus
Pathogens, 2021 Trends associated with codon usage in molluscum contagiosum virus (MCV) and factors governing the evolution of codon usage have not been investigated so far.
Rahul Raveendran Nair +4 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Pesquisa Veterinária Brasileira: Despite common occurrence and importance of canine distemper disease the majority of tests currently available for diagnosis are hampered by either low sensitivity or specificity. In this study it was evaluated antigenic and immunogenic characteristics
Maureen H.V. Fernandes +6 more
doaj +1 more source
Identification and characterization of Daldinia eschscholtzii isolated from skin scrapings, nails, and blood [PDF]
PeerJ, 2016 Background Daldinia eschscholtzii is a filamentous wood-inhabiting endophyte commonly found in woody plants. Here, we report the identification and characterization of nine D. eschscholtzii isolates from skin scrapings, nail clippings, and blood. Methods
Kee Peng Ng +9 more
doaj +2 more sources
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Microbial Cell Factories, 2021 Background Codon optimization is a common method to improve protein expression levels in Pichia pastoris and the current strategy is to replace rare codons with preferred codons to match the codon usage bias.
Yide Huang +6 more
doaj +1 more source