Results 1 to 10 of about 158,650 (268)

Peripheral Neuropathy Phenotyping in Rat Models of Type 2 Diabetes Mellitus: Evaluating Uptake of the Neurodiab Guidelines and Identifying Future Directions [PDF]

open access: yesDiabetes & Metabolism Journal, 2022
Diabetic peripheral neuropathy (DPN) affects over half of type 2 diabetes mellitus (T2DM) patients, with an urgent need for effective pharmacotherapies.
Md Jakir Hossain   +4 more
doaj   +1 more source

Preliminary study on the efficacy of rituximab in the treatment of idiopathic membranous nephropathy: A single-centre experience

open access: yesFrontiers in Endocrinology, 2023
ObjectiveTo investigate the efficacy of rituximab in the treatment of idiopathic membranous nephropathy (IMN).MethodsA total of 77 patients with IMN diagnosed in both our hospital and other hospitals were included in this study; the patients were divided
Ping Chen   +15 more
doaj   +1 more source

Graphical chain models for the analysis of complex genetic diseases: an application to hypertension [PDF]

open access: yes, 2002
A crucial task in modern genetic medicine is the understanding of complex genetic diseases. The main complicating features are that a combination of genetic and environmental risk factors is involved, and the phenotype of interest may be complex ...
Vicard, P., Di Serio, C.
core   +1 more source

Genetic analysis of environmental variation [PDF]

open access: yes, 2010
Environmental variation (V-E) in a quantitative trait - variation in phenotype that cannot be explained by genetic variation or identifiable genetic differences - can be regarded as being under some degree of genetic control. Such variation may be either
HAN A. MULDER   +5 more
core   +1 more source

Perfect Simulation From Nonneutral Population Genetic Models: Variable Population Size and Population Subdivision. [PDF]

open access: yes, 2006
We show how the idea of monotone coupling from the past can produce simple algorithms for simulating samples at a nonneutral locus under a range of demographic models.
Fearnhead, Paul, Paul Fearnhead
core   +1 more source

Genetic Inheritance Models of Non-Syndromic Cleft Lip with or without Palate: From Monogenic to Polygenic

open access: yes, 2023
Non-syndromic cleft lip with or without palate (NSCL/P) is a prevalent birth defect that affects 1/500–1/1400 live births globally. The genetic basis of NSCL/P is intricate and involves both genetic and environmental factors. In the past few years,
Fengzhou Du   +3 more
core   +1 more source

Discovering predictive variables when evolving cognitive models [PDF]

open access: yes, 2005
A non-dominated sorting genetic algorithm is used to evolve models of learning from different theories for multiple tasks. Correlation analysis is performed to identify parameters which affect performance on specific tasks; these are the predictive ...
Fernand Gobet   +5 more
core   +1 more source

Genetic algorithms for the generation of models with micropopulations [PDF]

open access: yes, 2003
Proceedings of: EvoWorkshops 2003: EvoBIO, EvoCOP, EvoIASP, EvoMUSART, EvoROB, and EvoSTIM Essex, UK, April 14–16, 2003The present article puts forward a method for an interactive model generation through the use of Genetic Algorithms applied to small ...
Sáez, Yago   +5 more
core   +1 more source

Statistical validation of genetic models

open access: yes, 2001
Various aspects of statistical validation of genetic models are reviewed. Possible ways of decomposing additive genetic variance over time and ways of comparing predictions at different times are suggested.
Robin Thompson, Thompson, R.
core   +1 more source

The Neolithic transition in Europe: archaeological models and genetic evidence

open access: yes, 2003
The major pattern in the European gene pool is a southeast-northwest frequency gradient of classic genetic markers such as blood groups, which population geneticists initially attributed to the demographic impact of Neolithic farmers dispersing from the ...
Richards, Martin   +2 more
core   +1 more source

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