Results 21 to 30 of about 158,650 (268)

Genetic heterogeneity of residual variance - estimation of variance components using double hierarchical generalized linear models

open access: yes, 2010
Background The sensitivity to microenvironmental changes varies among animals and may be under genetic control. It is essential to take this element into account when aiming at breeding robust farm animals.
Erling Strandberg   +21 more
core   +1 more source

Genetic prediction of male pattern baldness based on large independent datasets [PDF]

open access: yes, 2023
Genetic prediction of male pattern baldness (MPB) is important in science and society. Previous genetic MPB prediction models were limited by sparse marker coverage, small sample size, and/or data dependency in the different analytical steps.
Maj, Carlo   +6 more
core   +1 more source

Structured antedependence models for genetic analysis of repeated measures on multiple quantitative traits

open access: yes, 2003
Simultaneous analysis of correlated traits that change with time is an important issue in genetic analyses. Several methodologies have already been proposed for the genetic analysis of longitudinal data on single traits, in particular random regression ...
Hill, W. G., Jaffrezic, F., Thompson, R.
core   +1 more source

On using surrogates with genetic programming [PDF]

open access: yes, 2014
One way to accelerate evolutionary algorithms with expensive fitness evaluations is to combine them with surrogate models. Surrogate models are efficiently computable approximations of the fitness function, derived by means of statistical or machine ...
Branke, Jürgen, Hildebrandt, Torsten
core   +1 more source

Genetic model misspecification in genetic association studies [PDF]

open access: yesBMC Research Notes, 2017
The underlying model of the genetic determinant of a trait is generally not known with certainty a priori. Hence, in genetic association studies, a dominant model might be erroneously modelled as additive, an error investigated previously. We explored this question, for candidate gene studies, by evaluating the sample size required to compensate for ...
Amadou Gaye, Sharon K. Davis
openaire   +3 more sources

Fused in sarcoma (FUS) inhibits milk production efficiency in mammals

open access: yesNature Communications
Efficient milk production in mammals confers evolutionary advantages by facilitating the transmission of energy from mother to offspring. However, the regulatory mechanism responsible for the gradual establishment of milk production efficiency in mammals,
Haili Shao   +15 more
doaj   +1 more source

Controlling the uncontrolled variation in the diet induced obese mouse by microbiomic characterization

open access: yesScientific Reports, 2022
Group sizes in an animal study are calculated from estimates on variation, effect, power and significance level. Much of the variation in glucose related parameters of the diet-induced obese (DIO) mouse model is due to inter-individual variation in gut ...
Valeriia Bondarenko   +9 more
doaj   +1 more source

Rule-based models of the interplay between genetic and environmental factors in childhood allergy [PDF]

open access: yes, 2013
Both genetic and environmental factors are important for the development of allergic diseases. However, a detailed understanding of how such factors act together is lacking. To elucidate the interplay between genetic and environmental factors in allergic
Erik Melén (276082)   +81 more
core   +1 more source

A Genetic Algorithm for Automated Parameterization of Network Hamiltonian Models of Amyloid Fibril Formation

open access: yes, 2023
The timescales of long-time atomistic molecular dynamics simulations are typically reported in microseconds, while the timescales for experiments studying the kinetics of amyloid fibril formation are typically reported in minutes or hours. This timescale
Patrick, Regan   +3 more
core   +1 more source

Carcinomas and Carcinoid Tumors of the Lungs and Bronchi in Children and Adolescents: The EXPeRT Recommendations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele   +19 more
wiley   +1 more source

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