Results 41 to 50 of about 1,458,211 (268)

Efficient Derivation and Transcriptional Characterization of Mouse Extra-Embryonic Endoderm Stem Cell Lines Generated by Somatic Cell Nuclear Transfer

Stem Cells International
Somatic cell nuclear transfer (SCNT) holds great promise for regenerative medicine and agriculture, but its application is severely hampered by low efficiency, primarily attributable to aberrant epigenetic reprogramming.
Shuaipeng Li, Shu Wei, Guomeng Li, Mei Hu, Jiangwei Lin, Wandong Bao   +5 more
doaj   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

A high-quality genome assembly of the Spectacled Fulvetta (Fulvetta ruficapilla) endemic to China

Scientific Data
The Spectacled Fulvetta (Fulvetta ruficapilla) is the type species of Fulvetta, an evolutionarily distinct group whose species show a high degree of sympatry in distribution and phenotypic convergence.
Chen Yan, Si Si, Hong-Man Chen, Yu-Ting Zhang, Lu-Ming Liu, Fei Wu, Ming-Shan Wang   +6 more
doaj   +1 more source

Controlling the uncontrolled variation in the diet induced obese mouse by microbiomic characterization

Scientific Reports, 2022
Group sizes in an animal study are calculated from estimates on variation, effect, power and significance level. Much of the variation in glucose related parameters of the diet-induced obese (DIO) mouse model is due to inter-individual variation in gut ...
Valeriia Bondarenko, Cecillie Reynolds Løkke, Peter Dobrowolski, Caroline Junker Mentzel, Josué L. Castro-Mejía, Camilla Hartmann Friis Hansen, Dorte Bratbo Sørensen, Dennis Sandris Nielsen, Lukasz Krych, Axel Kornerup Hansen   +9 more
doaj   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Chromosome-level genome assembly of stem borer Batocera rufomaculata using PacBio HiFi and Hi-C sequencing

Scientific Data
Batocera rufomaculata (Cerambycidae: Lamiinae), a prominent representative of longhorned beetles, is a globally significant stem-boring pest, infesting over 50 species of deciduous trees.
Jinwu He, Tianqi Bai, Wenting Wan, Zhiwei Dong, Yangjie Wang, Hongrui Zhang, Xueyan Li   +6 more
doaj   +1 more source

Behavioral Convergence with Physiological Divergence: Sex Differences in Hormones but Not Social Behavior in Beagle Dogs

Animals
The “experimenter gender effect” is a pervasive confound in rodent behavioral neuroscience: the sex of the human handler alters stress, social, and pharmacological responses via olfactory cues and conserved neural circuits. Whether this effect extends to
Yu-Huan Xiao, Zi-Hua Zhao, Xue-Yan Jiang, Jun Zhang, Wen-Bing He, Rui Dong, Xue-Ting Zhang, Li-Xian Tao, Jun-Lv Ma, Jin-Xiu Li, Ya-Ping Zhang   +10 more
doaj   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

RNF220 safeguards meiotic synapsis and male fertility by antagonizing SYCE1 ubiquitination

Cell Death and Disease
A homozygous mutation in RNF220, encoding a RING-type E3 ubiquitin ligase, is associated with male infertility featuring small-headed sperm, but the precise roles and mechanisms of RNF220 in spermatogenesis remain elusive.
Jingmei Cha, Huijuan Lin, Yingqian Xia, Jianlin Xu, Pengcheng Ma, Shuhua Zhao, Bingyu Mao   +6 more
doaj   +1 more source

Transferring Face Recognition Techniques to Entomology: An ArcFace and ResNet Approach for Improving Dragonfly Classification

Applied Sciences
Dragonfly classification is crucial for biodiversity conservation. Traditional taxonomic approaches require extensive training and experience, limiting their efficiency. Computer vision offers promising solutions for dragonfly taxonomy. In this study, we
Zhong Li, Shaoyan Pu, Jingsheng Lu, Ruibin Song, Haomiao Zhang, Xuemei Lu, Yanan Wang   +6 more
doaj   +1 more source