Results 41 to 50 of about 9,816,038 (309)

DNA replication fork speed acts as a pacer in cortical neurogenesis

Nature Communications
DNA replication fork speed, which controls the rate of genome duplication, has emerged as a key regulator of cellular plasticity. However, its role in neurogenesis remains unexplored.
Jianhong Wang, Yifan Kong, Xuezhuang Li, Dexi Chen, Kun Xiang, Yulian Tan, Lei Shi   +6 more
doaj   +1 more source

Stochastic modelling of Genetic Algorithms

Artificial Intelligence, 1996
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
David Reynolds, Jagannathan Gomatam
openaire   +3 more sources

Acute Neurological Events in Children With Hemoglobin SC Disease: A Multicenter Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurological manifestations in children with hemoglobin SC (HbSC) disease remain insufficiently characterized, particularly regarding acute events. The aim of this study was to describe the spectrum and frequency of acute neurological events in a multicenter cohort of children with HbSC disease.
Célia Paulmin, Bérengère Koehl, Audrey Maudoux, Hanine Mansour, Marie‐Hélène Odievre, Nathalie Garrec, Emilie Georget, Cécile Arnaud, Slimane Allali, Lydia Doumdo, Marie Belloy, Corinne Guitton   +11 more
wiley   +1 more source

Chromosome-level genome of Cyprinus rubrofuscus ♀ × Sinocyclocheilus grahami ♂ provides high-quality parental haplotype genomes and insights into hybrid economic traits enhancement

BMC Genomics
Cyprinids, the largest and most economically significant family of teleosts, comprise over 600 polyploid species, whose genomic complexity presents challenges in deciphering the genetic basis of phenotypic diversity.
Yanhui Yin, Yuanwei Zhang, Anli Wu, Wei Dao, Jing Long, Xiaofu Pan, Junxing Yang, Xiaoai Wang   +7 more
doaj   +1 more source

Controlling the uncontrolled variation in the diet induced obese mouse by microbiomic characterization

Scientific Reports, 2022
Group sizes in an animal study are calculated from estimates on variation, effect, power and significance level. Much of the variation in glucose related parameters of the diet-induced obese (DIO) mouse model is due to inter-individual variation in gut ...
Valeriia Bondarenko, Cecillie Reynolds Løkke, Peter Dobrowolski, Caroline Junker Mentzel, Josué L. Castro-Mejía, Camilla Hartmann Friis Hansen, Dorte Bratbo Sørensen, Dennis Sandris Nielsen, Lukasz Krych, Axel Kornerup Hansen   +9 more
doaj   +1 more source

Genetic Models of Leukemia in Zebrafish [PDF]

Frontiers in Cell and Developmental Biology, 2018
The zebrafish animal model is gaining increasing popularity as a tool for studying human disease. Over the past 15 years, many models of leukemia and other hematological malignancies have been developed in the zebrafish. These confer some significant advantages over similar models in other animals and systems, representing a powerful resource for ...
Jeremy T. Baeten, Jill L. O. de Jong
openaire   +3 more sources

Infant Embryonal CNS Tumors: Molecular Insights and Treatment Considerations for Contemporary Pediatric Neuro‐Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan, Mariah Wright‐Nadkarni, Mohamed S. Abdelbaki, Girish Dhall   +3 more
wiley   +1 more source

Structured antedependence models for genetic analysis of repeated measures on multiple quantitative traits

, 2003
Simultaneous analysis of correlated traits that change with time is an important issue in genetic analyses. Several methodologies have already been proposed for the genetic analysis of longitudinal data on single traits, in particular random regression ...
Hill, W. G., Jaffrezic, F., Thompson, R.
core   +1 more source

Genetic influences on exercise participation in 37.051 twin pairs from seven countries [PDF]

, 2006
Background A sedentary lifestyle remains a major threat to health in contemporary societies. To get more insight in the relative contribution of genetic and environmental influences on individual differences in exercise participation, twin samples from ...
Hunkin, J, Boomsma, Dorret I, Spector Tim D., Kaprio J, Nicholas G. Martin, Martin NG, Harris, Jennifer R., de Geus, Eco J. C, Belinda K. Cornes, Rose, Richard J., Eco J. C. De Geus, de Geus, E.J.C., Stubbe JH, Dorret I. Boomsma, Richard J, Harris JR, Stubbe Janine H., Kyvik, KO, Rose RJ, Pedersen, Nancy L., Martin, N.G., de Geus EJ, Tim D Spector, de Geus Eco J.C., Boomsma, Dorret I., Pedersen, Nancy L, Nancy L Pedersen, Cornes, Belinda K, Kaprio, Jaakko, Skytthe A, Martin, Nicholas G., Stubbe, Janine H., Kyvik, K., Vink, JM, Hunkin Janice, Rose, Richard J, Rose, RJ, Jacqueline M. Vink, Vink JM, Skytthe, Axel, Pedersen NL, Dorret I Boomsma, Vink, J.M., Hunkin, J., Vink, Jacqueline M., de Geus, EJC, Kujala, Urho M, Jennifer R Harris, Kyvik KO, Boomsma DI, Boomsma, DI, Kujala UM, Cornes, Belinda K., Kaprio, J., Kyvik, Kirsten O., Richard J Rose, Jennifer R. Harris, Axel Skytthe, Spector, Tim D, Nancy L. Pedersen, Rose Richard J., Kujala, UM, Stubbe, JH, Skytthe, A, Eco J C de Geus, Kirsten O. Kyvik, Kyvik Kirsten O., Harris Jennifer R., Janice Hunkin, Boomsma Dorret I., Skytthe Axel, Vink Jacqueline M., Spector TD, Kirsten O Kyvik, Kujala, U., Kaprio Jaakko, Stubbe, Janine H, Pedersen, N.L., Martin, NG, Kujala, Urho M., Cornes Belinda K., Urho M. Kujala, Harris, Jennifer R, Spector, T.D., Jaakko Kaprio, Pedersen, NL, Stubbe, J.H., Boomsma, D.I., Martin Nicholas G., Cornes BK, Tim D. Spector, de Geus, E.J.C.; id_orcid, de Geus, EJ, Harris, JR, Vink, Jacqueline M, Kyvik, Kirsten O, Cornes, B., Belinda K Cornes, Urho M Kujala, Rose, R.J., Spector, Tin D., Skytthe, A., Pedersen Nancy L., Martin, Nicholas G, Kaprio, J, Janine H Stubbe, Cornes, BK, De Geus, Eco J. C., Hunkin J, Nicholas G Martin, Jacqueline M Vink, Spector, TD, Hunkin, Janice, Boomsma, D.I.; id_orcid, Harris, J.R., Janine H. Stubbe, Kujala Urho M.   +116 more
core   +3 more sources

Provider and Parent Perspectives on Prioritizing the “Asking and Monitoring” Pediatric Cancer Psychosocial Standards of Care

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Standards for Psychosocial Care for Children with Cancer and Their Families (“Standards”) are evidence‐based guidelines for psychosocial care in pediatric oncology. Care related to the three “Asking and Monitoring” Standards—Assessment of Psychosocial Needs, Assessment of Financial Needs, and Monitoring Neurocognitive Problems ...
Julia B. Tager, Natalie Koskela‐Staples, Emily M. Pariseau, Michele Scialla, Kimberly Buff, Lori Wiener, Victoria Sardi Brown, Anne E. Kazak, Kimberly S. Canter   +8 more
wiley   +1 more source