Results 51 to 60 of about 28,946,101 (334)

A high-quality genome assembly of the Spectacled Fulvetta (Fulvetta ruficapilla) endemic to China

Scientific Data
The Spectacled Fulvetta (Fulvetta ruficapilla) is the type species of Fulvetta, an evolutionarily distinct group whose species show a high degree of sympatry in distribution and phenotypic convergence.
Chen Yan, Si Si, Hong-Man Chen, Yu-Ting Zhang, Lu-Ming Liu, Fei Wu, Ming-Shan Wang   +6 more
doaj   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

Discrete time piecewise affine models of genetic regulatory networks [PDF]

, 2005
We introduce simple models of genetic regulatory networks and we proceed to the mathematical analysis of their dynamics. The models are discrete time dynamical systems generated by piecewise affine contracting mappings whose variables represent gene ...
A. Meyroneinc, B. Fern, Lisboa Codex, R. Coutinho, R. Lima   +4 more
core   +1 more source

Chromosome-level genome assembly of stem borer Batocera rufomaculata using PacBio HiFi and Hi-C sequencing

Scientific Data
Batocera rufomaculata (Cerambycidae: Lamiinae), a prominent representative of longhorned beetles, is a globally significant stem-boring pest, infesting over 50 species of deciduous trees.
Jinwu He, Tianqi Bai, Wenting Wan, Zhiwei Dong, Yangjie Wang, Hongrui Zhang, Xueyan Li   +6 more
doaj   +1 more source

Targeting cuproptosis by zinc pyrithione in triple-negative breast cancer

iScience, 2023
Summary: Triple-negative breast cancer (TNBC) poses a considerable challenge due to its aggressive nature. Notably, metal ion-induced cell death, such as ferroptosis, has garnered significant attention and demonstrated potential implications for cancer ...
Xu Yang, Li Deng, Xianhong Diao, Siyuan Yang, Li Zou, Qin Yang, Jian Li, Jianyun Nie, Lina Zhao, Baowei Jiao   +9 more
doaj   +1 more source

Animal models of atherosclerosis

Biomedical Reports, 2017
Atherosclerosis is a significant cause of morbidity and mortality globally. Many animal models have been developed to study atherosclerosis, and permit experimental conditions, diet and environmental risk factors to be carefully controlled ...
Yee Ting Lee, V. Laxton, Hiu Yu Lin, Y. W. Chan, Sophia A M Fitzgerald-Smith, T. L. To, B. Yan, Tong Liu, G. Tse   +8 more
semanticscholar   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Artificial Intelligence Revolution in Transcriptomics: From Single Cells to Spatial Atlases

Advanced Science
Single‐cell RNA sequencing (scRNA‐seq) and spatial transcriptomics (ST) have revolutionized the study of cellular heterogeneity and tissue organization.
Shixin Li, Tianxiang Xiao, Yuanyuan Lan, Chengxiao Wu, Zhouying Li, Rong Liu, Qing Fang, Chao Zhang   +7 more
doaj   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

NEK4 modulates circadian fluctuations of emotional behaviors and synaptogenesis in male mice

Nature Communications
GWASs have linked the 3p21.1 locus, which is associated with the expression levels of NEK4, to bipolar disorder. Here, we use integrative analyses of GWAS statistics and eQTL annotations to establish that elevated NEK4 expression in the hippocampus is ...
Zhi-Hui Yang, Xin Cai, Chu-Yi Zhang, Qing Zhang, Miao Li, Zhong-Li Ding, Yingqi Guo, Guolan Ma, Chao-Hao Yang, Lei Guo, Hong Chang, Chuang Wang, Ming Li, Xiao Xiao   +13 more
doaj   +1 more source