The Neolithic transition in Europe: archaeological models and genetic evidence [PDF]
, 2003 The major pattern in the European gene pool is a southeast-northwest frequency gradient of classic genetic markers such as blood groups, which population geneticists initially attributed to the demographic impact of Neolithic farmers dispersing from the ...
Richards, Martin +2 more
core +2 more sources
Genetic heterogeneity of residual variance - estimation of variance components using double hierarchical generalized linear models [PDF]
, 2010 Background The sensitivity to microenvironmental changes varies among animals and may be under genetic control. It is essential to take this element into account when aiming at breeding robust farm animals.
Erling Strandberg +21 more
core +1 more source
Structured antedependence models for genetic analysis of repeated measures on multiple quantitative traits [PDF]
, 2003 Simultaneous analysis of correlated traits that change with time is an important issue in genetic analyses. Several methodologies have already been proposed for the genetic analysis of longitudinal data on single traits, in particular random regression ...
Hill, W. G., Jaffrezic, F., Thompson, R.
core +1 more source
Graphical chain models for the analysis of complex genetic diseases: an application to hypertension [PDF]
, 2002 A crucial task in modern genetic medicine is the understanding of complex genetic diseases. The main complicating features are that a combination of genetic and environmental risk factors is involved, and the phenotype of interest may be complex ...
Vicard, P., Di Serio, C.
core +1 more source
A Genetic Algorithm for Automated Parameterization of Network Hamiltonian Models of Amyloid Fibril Formation [PDF]
, 2023 The timescales of long-time atomistic molecular dynamics simulations are typically reported in microseconds, while the timescales for experiments studying the kinetics of amyloid fibril formation are typically reported in minutes or hours. This timescale
Patrick, Regan +3 more
core +1 more source
A COMPARISON OF GENETIC NETWORK MODELS [PDF]
Biocomputing 2001, 2000 With the completion of the sequencing of the human genome, the need for tools capable of unraveling the interaction and functionality of genes becomes extremely urgent. In answer to this quest, the advent of microarray technology provides the opportunity to perform large scale gene expression analyses.
Lodewyk F. A. Wessels +2 more
openaire +2 more sources
Genetic analysis of environmental variation [PDF]
, 2010 Environmental variation (V-E) in a quantitative trait - variation in phenotype that cannot be explained by genetic variation or identifiable genetic differences - can be regarded as being under some degree of genetic control. Such variation may be either
HAN A. MULDER +5 more
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Perfect Simulation From Nonneutral Population Genetic Models: Variable Population Size and Population Subdivision. [PDF]
, 2006 We show how the idea of monotone coupling from the past can produce simple algorithms for simulating samples at a nonneutral locus under a range of demographic models.
Fearnhead, Paul, Paul Fearnhead
core +1 more source
Discovering predictive variables when evolving cognitive models [PDF]
, 2005 A non-dominated sorting genetic algorithm is used to evolve models of learning from different theories for multiple tasks. Correlation analysis is performed to identify parameters which affect performance on specific tasks; these are the predictive ...
Fernand Gobet +5 more
core +1 more source
, 2019 Genetically altered rat and mouse models have been instrumental in the functional analysis of genes in a physiological context. In particular, studies on the renin-angiotensin system (RAS) have profited from this technology in the past. In this review, we summarize the existing animal models for the protective axis of the RAS consisting of angiotensin ...
Alenina, Natalia, Bader, Michael
openaire +2 more sources