Results 1 to 10 of about 1,318 (167)

Eukaryotic evolutionary transitions are associated with extreme codon bias in functionally-related proteins. [PDF]

open access: yesPLoS ONE, 2011
Codon bias in the genome of an organism influences its phenome by changing the speed and efficiency of mRNA translation and hence protein abundance. We hypothesized that differences in codon bias, either between-species differences in orthologous genes ...
Nicholas J Hudson   +5 more
doaj   +1 more source

Codon Usage Bias in Phytoplankton

open access: yesJournal of Marine Science and Engineering, 2022
Non-random usage of synonymous codons, known as “codon bias”, has been described in many organisms, from bacteria to Drosophila, but little is known about it in phytoplankton.
Marc Krasovec, Dmitry A. Filatov
doaj   +1 more source

Causes and implications of codon usage bias in RNA viruses. [PDF]

open access: yesPLoS ONE, 2013
Choice of synonymous codons depends on nucleotide/dinucleotide composition of the genome (termed mutational pressure) and relative abundance of tRNAs in a cell (translational pressure).
Ilya S Belalov, Alexander N Lukashev
doaj   +1 more source

Analysis of codon usage pattern in Lonicera × heckrottii ‘Gold Flame’ based on chloroplast genome

open access: yesNotulae Botanicae Horti Agrobotanici Cluj-Napoca, 2022
Codon usage bias (CUB) was a unique feature of the genome, and revealing chloroplast genome codon usage bias can provide useful information for the evolution of plant species.
Jiaqiang ZHANG   +3 more
doaj   +1 more source

Comprehensive analysis of codon bias in 13 Ganoderma mitochondrial genomes

open access: yesFrontiers in Microbiology, 2023
IntroductionCodon usage bias is a prevalent phenomenon observed across various species and genes. However, the specific attributes of codon usage in the mitochondrial genome of Ganoderma species remain unknown.MethodsIn this study, we investigated the ...
Peng Wu   +8 more
doaj   +1 more source

Comparative analysis of codon usage bias and codon context patterns between dipteran and hymenopteran sequenced genomes. [PDF]

open access: yesPLoS ONE, 2012
Codon bias is a phenomenon of non-uniform usage of codons whereas codon context generally refers to sequential pair of codons in a gene. Although genome sequencing of multiple species of dipteran and hymenopteran insects have been completed only a few of
Susanta K Behura, David W Severson
doaj   +1 more source

Comparative analysis of codon usage patterns of FUT2 from different species

open access: yesKuwait Journal of Science, 2022
Enterotoxigenic E. coli is an important zoonotic pathogen causing diarrhea in human and newborn animals. α - (1,2) fucosyltransferase 2 (FUT2) is closely associated with the formation of pathogenic receptors of Enterotoxigenic E. coli.
Chao Xu   +3 more
doaj   +1 more source

Identification of the optimal codons for acetolactate synthase from weeds: an in-silico study

open access: yesPlant, Soil and Environment, 2021
Although various studies of codon usage bias have been reported in a broad spectrum of organisms, no studies to date have examined codon usage bias for herbicide target genes. In this study, we analysed codon usage patterns for the acetolactate synthase (
Madhab Kumar Sen   +3 more
doaj   +1 more source

Codon pair optimization (CPO): a software tool for synthetic gene design based on codon pair bias to improve the expression of recombinant proteins in Pichia pastoris

open access: yesMicrobial Cell Factories, 2021
Background Codon optimization is a common method to improve protein expression levels in Pichia pastoris and the current strategy is to replace rare codons with preferred codons to match the codon usage bias.
Yide Huang   +6 more
doaj   +1 more source

Codon-based indices for modeling gene expression and transcript evolution

open access: yesComputational and Structural Biotechnology Journal, 2021
Codon usage bias (CUB) refers to the phenomena that synonymous codons are used in different frequencies in most genes and organisms. The general assumption is that codon biases reflect a balance between mutational biases and natural selection.
Shir Bahiri-Elitzur, Tamir Tuller
doaj   +1 more source

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