Results 31 to 40 of about 96,165 (278)
Microbial Cell Factories, 2021 Background Codon optimization is a common method to improve protein expression levels in Pichia pastoris and the current strategy is to replace rare codons with preferred codons to match the codon usage bias.
Yide Huang +6 more
doaj +1 more source
Identification of the optimal codons for acetolactate synthase from weeds: an in-silico study
Plant, Soil and Environment, 2021 Although various studies of codon usage bias have been reported in a broad spectrum of organisms, no studies to date have examined codon usage bias for herbicide target genes. In this study, we analysed codon usage patterns for the acetolactate synthase (
Madhab Kumar Sen +3 more
doaj +1 more source
Codon-based indices for modeling gene expression and transcript evolution
Computational and Structural Biotechnology Journal, 2021 Codon usage bias (CUB) refers to the phenomena that synonymous codons are used in different frequencies in most genes and organisms. The general assumption is that codon biases reflect a balance between mutational biases and natural selection.
Shir Bahiri-Elitzur, Tamir Tuller
doaj +1 more source
Codon usage and codon context bias in Xanthophyllomyces dendrorhous [PDF]
BMC Genomics, 2015 Synonymous codons are used differentially in organisms from the three domains of life, a phenomenon referred to as codon usage bias. In addition, codon pair bias, particularly in the 3' codon context, has also been described in several organisms and is associated with the accuracy and rate of translation. An improved understanding of both types of bias
Baeza Cancino, Marcelo +4 more
openaire +5 more sources
The Codon Statistics Database: A Database of Codon Usage Bias
Molecular Biology and Evolution, 2022 Abstract We present the Codon Statistics Database, an online database that contains codon usage statistics for all the species with reference or representative genomes in RefSeq (over 15,000). The user can search for any species and access two sets of tables.
Krishnamurthy Subramanian +3 more
openaire +2 more sources
Distinct responses to rare codons in select Drosophila tissues
eLife, 2022 Codon usage bias has long been appreciated to influence protein production. Yet, relatively few studies have analyzed the impacts of codon usage on tissue-specific mRNA and protein expression.
Scott R Allen +8 more
doaj +1 more source
Codon Bias as a Means to Fine-Tune Gene Expression. [PDF]
Mol Cell, 2015 Quax TE +3 more
europepmc +2 more sources
Clustering of classical swine fever virus isolates by codon pair bias
BMC Research Notes, 2011 Background The genetic code consists of non-random usage of synonymous codons for the same amino acids, termed codon bias or codon usage. Codon juxtaposition is also non-random, referred to as codon context bias or codon pair bias.
Leifer Immanuel +4 more
doaj +1 more source
Codon Usage of Hepatitis E Viruses: A Comprehensive Analysis
Frontiers in Microbiology, 2022 Hepatitis E virus (HEV) is an emerging zoonotic pathogen with multiple species and genotypes, which may be classified into human, animal, and zoonotic HEV. Codon usage bias of HEV remained unclear.
Bingzhe Li +5 more
doaj +1 more source
Quantitative relationship between synonymous codon usage bias and GC composition across unicellular genomes [PDF]
, 2004 Background Codon usage bias has been widely reported to correlate with GC composition. However, the quantitative relationship between codon usage bias and GC composition across species has not been reported.
Xiu-Feng Wan +3 more
core +2 more sources