A general model of codon bias due to GC mutational bias.
PLoS ONE, 2010 BackgroundIn spite of extensive research on the effect of mutation and selection on codon usage, a general model of codon usage bias due to mutational bias has been lacking.
Gareth A Palidwor +2 more
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On ribosome load, codon bias and protein abundance. [PDF]
PLoS ONE, 2012 Different codons encoding the same amino acid are not used equally in protein-coding sequences. In bacteria, there is a bias towards codons with high translation rates.
Stefan Klumpp, Jiajia Dong, Terence Hwa
doaj +2 more sources
Codon bias among synonymous rare variants is associated with Alzheimer's disease imaging biomarker. [PDF]
Pac Symp Biocomput, 2018 Alzheimer's disease (AD) is a neurodegenerative disorder with few biomarkers even though it impacts a relatively large portion of the population and is predicted to affect significantly more individuals in the future.
Miller JE +6 more
europepmc +3 more sources
Relative Codon Adaptation: A Generic Codon Bias Index for Prediction of Gene Expression [PDF]
DNA Research, 2010 The development of codon bias indices (CBIs) remains an active field of research due to their myriad applications in computational biology. Recently, the relative codon usage bias (RCBS) was introduced as a novel CBI able to estimate codon bias without using a reference set.
Fox, Jesse M., Erill, Ivan
openaire +5 more sources
Eukaryotic evolutionary transitions are associated with extreme codon bias in functionally-related proteins. [PDF]
PLoS ONE, 2011 Codon bias in the genome of an organism influences its phenome by changing the speed and efficiency of mRNA translation and hence protein abundance. We hypothesized that differences in codon bias, either between-species differences in orthologous genes ...
Nicholas J Hudson +5 more
doaj +1 more source
Causes and implications of codon usage bias in RNA viruses. [PDF]
PLoS ONE, 2013 Choice of synonymous codons depends on nucleotide/dinucleotide composition of the genome (termed mutational pressure) and relative abundance of tRNAs in a cell (translational pressure).
Ilya S Belalov, Alexander N Lukashev
doaj +1 more source
Comparative analysis of codon usage bias and codon context patterns between dipteran and hymenopteran sequenced genomes. [PDF]
PLoS ONE, 2012 Codon bias is a phenomenon of non-uniform usage of codons whereas codon context generally refers to sequential pair of codons in a gene. Although genome sequencing of multiple species of dipteran and hymenopteran insects have been completed only a few of
Susanta K Behura, David W Severson
doaj +1 more source
Analysis of codon usage pattern in Lonicera × heckrottii ‘Gold Flame’ based on chloroplast genome
Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 2022 Codon usage bias (CUB) was a unique feature of the genome, and revealing chloroplast genome codon usage bias can provide useful information for the evolution of plant species.
Jiaqiang ZHANG +3 more
doaj +1 more source
Comparative analysis of codon usage patterns of FUT2 from different species
Kuwait Journal of Science, 2022 Enterotoxigenic E. coli is an important zoonotic pathogen causing diarrhea in human and newborn animals. α - (1,2) fucosyltransferase 2 (FUT2) is closely associated with the formation of pathogenic receptors of Enterotoxigenic E. coli.
Chao Xu +3 more
doaj +1 more source
Codon usage bias in radioresistant bacteria [PDF]
Gene, 2020 AbstractThe relationship between patterns of codon usage bias (CUB), the preferential usage of synonimous nucleotide triplets encoding the same amino acid, and radioresistance was investigated int he genomes of 16 taxonomically distinct radioresistant prokaryotic organisms and in a control set of 11 non-radioresistant bacteria.
Dilucca M. +3 more
openaire +4 more sources