Results 21 to 30 of about 52,855 (250)
Eukaryotic evolutionary transitions are associated with extreme codon bias in functionally-related proteins. [PDF]
PLoS ONE, 2011 Codon bias in the genome of an organism influences its phenome by changing the speed and efficiency of mRNA translation and hence protein abundance. We hypothesized that differences in codon bias, either between-species differences in orthologous genes ...
Nicholas J Hudson +5 more
doaj +1 more source
Causes and implications of codon usage bias in RNA viruses. [PDF]
PLoS ONE, 2013 Choice of synonymous codons depends on nucleotide/dinucleotide composition of the genome (termed mutational pressure) and relative abundance of tRNAs in a cell (translational pressure).
Ilya S Belalov, Alexander N Lukashev
doaj +1 more source
The Codon Statistics Database: A Database of Codon Usage Bias
Molecular Biology and Evolution, 2022 Abstract We present the Codon Statistics Database, an online database that contains codon usage statistics for all the species with reference or representative genomes in RefSeq (over 15,000). The user can search for any species and access two sets of tables.
Krishnamurthy Subramanian +3 more
openaire +2 more sources
Analysis of codon usage pattern in Lonicera × heckrottii ‘Gold Flame’ based on chloroplast genome
Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 2022 Codon usage bias (CUB) was a unique feature of the genome, and revealing chloroplast genome codon usage bias can provide useful information for the evolution of plant species.
Jiaqiang ZHANG +3 more
doaj +1 more source
Comparative analysis of codon usage bias and codon context patterns between dipteran and hymenopteran sequenced genomes. [PDF]
PLoS ONE, 2012 Codon bias is a phenomenon of non-uniform usage of codons whereas codon context generally refers to sequential pair of codons in a gene. Although genome sequencing of multiple species of dipteran and hymenopteran insects have been completed only a few of
Susanta K Behura, David W Severson
doaj +1 more source
Comparative analysis of codon usage patterns of FUT2 from different species
Kuwait Journal of Science, 2022 Enterotoxigenic E. coli is an important zoonotic pathogen causing diarrhea in human and newborn animals. α - (1,2) fucosyltransferase 2 (FUT2) is closely associated with the formation of pathogenic receptors of Enterotoxigenic E. coli.
Chao Xu +3 more
doaj +1 more source
Codon usage and codon context bias in Xanthophyllomyces dendrorhous [PDF]
BMC Genomics, 2015 Synonymous codons are used differentially in organisms from the three domains of life, a phenomenon referred to as codon usage bias. In addition, codon pair bias, particularly in the 3' codon context, has also been described in several organisms and is associated with the accuracy and rate of translation. An improved understanding of both types of bias
Baeza Cancino, Marcelo +4 more
openaire +5 more sources
Microbial Cell Factories, 2021 Background Codon optimization is a common method to improve protein expression levels in Pichia pastoris and the current strategy is to replace rare codons with preferred codons to match the codon usage bias.
Yide Huang +6 more
doaj +1 more source
Identification of the optimal codons for acetolactate synthase from weeds: an in-silico study
Plant, Soil and Environment, 2021 Although various studies of codon usage bias have been reported in a broad spectrum of organisms, no studies to date have examined codon usage bias for herbicide target genes. In this study, we analysed codon usage patterns for the acetolactate synthase (
Madhab Kumar Sen +3 more
doaj +1 more source
Codon-based indices for modeling gene expression and transcript evolution
Computational and Structural Biotechnology Journal, 2021 Codon usage bias (CUB) refers to the phenomena that synonymous codons are used in different frequencies in most genes and organisms. The general assumption is that codon biases reflect a balance between mutational biases and natural selection.
Shir Bahiri-Elitzur, Tamir Tuller
doaj +1 more source