Results 11 to 20 of about 1,318 (167)

CBDB: The codon bias database

open access: yesBMC Bioinformatics, 2012
Background In many genomes, a clear preference in the usage of particular codons exists. The mechanisms that induce codon biases remain an open question; studies have attributed codon usage to translational selection, mutational bias and drift ...
Hilterbrand Adam   +2 more
doaj   +1 more source

Clustering of classical swine fever virus isolates by codon pair bias

open access: yesBMC Research Notes, 2011
Background The genetic code consists of non-random usage of synonymous codons for the same amino acids, termed codon bias or codon usage. Codon juxtaposition is also non-random, referred to as codon context bias or codon pair bias.
Leifer Immanuel   +4 more
doaj   +1 more source

Distinct responses to rare codons in select Drosophila tissues

open access: yeseLife, 2022
Codon usage bias has long been appreciated to influence protein production. Yet, relatively few studies have analyzed the impacts of codon usage on tissue-specific mRNA and protein expression.
Scott R Allen   +8 more
doaj   +1 more source

On ribosome load, codon bias and protein abundance. [PDF]

open access: yesPLoS ONE, 2012
Different codons encoding the same amino acid are not used equally in protein-coding sequences. In bacteria, there is a bias towards codons with high translation rates.
Stefan Klumpp, Jiajia Dong, Terence Hwa
doaj   +1 more source

Codon Usage of Hepatitis E Viruses: A Comprehensive Analysis

open access: yesFrontiers in Microbiology, 2022
Hepatitis E virus (HEV) is an emerging zoonotic pathogen with multiple species and genotypes, which may be classified into human, animal, and zoonotic HEV. Codon usage bias of HEV remained unclear.
Bingzhe Li   +5 more
doaj   +1 more source

A general model of codon bias due to GC mutational bias.

open access: yesPLoS ONE, 2010
BackgroundIn spite of extensive research on the effect of mutation and selection on codon usage, a general model of codon usage bias due to mutational bias has been lacking.
Gareth A Palidwor   +2 more
doaj   +1 more source

Codon Pair Bias Is a Direct Consequence of Dinucleotide Bias

open access: yesCell Reports, 2016
Codon pair bias is a remarkably stable characteristic of a species. Although functionally uncharacterized, robust virus attenuation was achieved by recoding of viral proteins using underrepresented codon pairs.
Dusan Kunec, Nikolaus Osterrieder
doaj   +1 more source

Analysis of synonymous codon usage patterns in mitochondrial genomes of nine Amanita species

open access: yesFrontiers in Microbiology, 2023
IntroductionCodon basis is a common and complex natural phenomenon observed in many kinds of organisms.MethodsIn the present study, we analyzed the base bias of 12 mitochondrial core protein-coding genes (PCGs) shared by nine Amanita species.ResultsThe ...
Qiang Li   +8 more
doaj   +1 more source

Codon Usage Bias Correlates With Gene Length in Neurodegeneration Associated Genes

open access: yesFrontiers in Neuroscience, 2022
Codon usage analysis is a crucial part of molecular characterization and is used to determine the factors affecting the evolution of a gene. The length of a gene is an important parameter that affects the characteristics of the gene, such as codon usage,
Rekha Khandia   +9 more
doaj   +1 more source

Codon Bias Patterns of E. coli's Interacting Proteins. [PDF]

open access: yesPLoS ONE, 2015
Synonymous codons, i.e., DNA nucleotide triplets coding for the same amino acid, are used differently across the variety of living organisms. The biological meaning of this phenomenon, known as codon usage bias, is still controversial.
Maddalena Dilucca   +4 more
doaj   +1 more source

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