Results 131 to 140 of about 486,575 (254)

The unique epigenetic features of Pack-MULEs and their impact on chromosomal base composition and expression spectrum. [PDF]

open access: yesNucleic Acids Res, 2018
Zhao D   +8 more
europepmc   +2 more sources

Composition of text repetition and parallelism on the base of A.P. Chekhov's stories

open access: yesRUDN Journal of Language Studies, Semiotics and Semantics, 2011
In the article on the base of materials from A.P. Chekhov's stories parallelisms and repetitions encountered at different levels of organization of speech in the text, I considered.
N V Nikashina
doaj  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Base composition at the start of the coding sequence controls the balance between translation initiation and mRNA degradation in E. coli. [PDF]

open access: yesNucleic Acids Res
Lipońska A   +8 more
europepmc   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Nucleosomal organization and DNA base composition patterns. [PDF]

open access: yesNucleus, 2017
García A, González S, Antequera F.
europepmc   +1 more source

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