Retrieving the vertical distribution of chlorophyll a concentration and phytoplankton community composition from in situ fluorescence profiles: A method based on a neural network with potential for global‐scale applications [PDF]
, 2015 Raphaëlle Sauzède +6 more
openalex +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Comparative Study of the Nutrient Composition of Four Varieties of Cowpea (Vigna unguiculata) and Their Products (Beans-Based Products) [PDF]
, 2015 G.T.O. Otitoju +3 more
openalex +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Unbiased Estimate of Synonymous and Nonsynonymous Substitution Rates with Nonstationary Base Composition. [PDF]
Mol Biol Evol, 2018 Guéguen L, Duret L.
europepmc +1 more source
Investigation of the emulsions based on functional food compositions containing protein
, 2015 Василь Миколайович Пасічний +2 more
openalex +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Physicians' patient base composition and mortality among people living with HIV who initiated antiretroviral therapy in a universal care setting. [PDF]
BMJ Open, 2019 Allan B +13 more
europepmc +1 more source