Results 91 to 100 of about 1,511,123 (311)

AN INVESTIGATION OF BASE ISOLATION

Selçuk Üniversitesi Mühendislik, Bilim ve Teknoloji Dergisi, 2012
The effect of weak shear rigidity is important in the analysis of elastomeric bearings used for base isolation of buildings. In particular, the buckling load is low and the P-Δ effect is significant as compared to standard columns neglecting shear deformations. In this paper, a simple mechanical model accounting for both shear and flexural deformations
openaire   +2 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Experimental Evaluation of Low-Pass Shock Isolation Performance of Elastomers Using Frequency-Based Kolsky Bar Analyses

, 2021
Brett Sanborn, Bo Song, Erik E Nishida, Marlene E. Knight   +3 more
openalex   +1 more source

Partial gravity habitat study: With application to lunar base design [PDF]

Comprehensive design requirements associated with designing habitats for humans in a partial gravity environment were investigated and then applied to a lunar base design.
Akhidime, Eval, Bell, Larry, Bunch, Michael, Capps, Stephen, Lorandos, Jason, Lund, Denise, Moore, Nathan, Murakawa, Kio, Neubek, Deb, Trotti, Guillermo   +9 more
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

3 V operation of pentacene-based floating-gate memory realized by the isolation process with Ar/N₂-plasma nitridation for N-doped LaB₆ metal and high-k LaB _x N_y insulator stacked structure [PDF]

, 2022
Eun-Ki Hong, Shun-ichiro Ohmi
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Bead Array–Based microRNA Expression Profiling of Peripheral Blood and the Impact of Different RNA Isolation Approaches [PDF]

, 2010
Andrea Gaarz, Svenja Debey‐Pascher, Sabine Claßen, Daniela Eggle, Birgit Gathof, Jing Chen, Jian‐Bing Fan, Thorsten Voß, Joachim L. Schultze, Andrea Staratschek‐Jox   +9 more
openalex   +1 more source

An Isolable Base‐Stabilized Diazosilenyl Cation

Angewandte Chemie
AbstractIn contrast to the emerging chemistry of stable diazoalkenes, there are not yet any studies devoted to heavier silicon analogues, diazosilenes. Here, we report the synthesis of a base‐stabilized diazosilenyl cation 2 by the reaction of base‐stabilized C‐phosphonio‐silyne 1 with N2O.
Shintaro Takahashi, Aurora Rodríguez‐Álvarez, Antoine Baceiredo, Pierre Lavedan, Nathalie Saffon‐Merceron, Vicenç Branchadell, Tsuyoshi Kato   +6 more
openaire   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source