Results 121 to 130 of about 34,309,087 (270)
GibbsCluster: unsupervised clustering and alignment of peptide sequences [PDF]
, 2017 Receptor interactions with short linear peptide fragments (ligands) are at the base of many biological signaling processes. Conserved and information-rich amino acid patterns, commonly called sequence motifs, shape and regulate these interactions ...
Alvarez, Bruno +2 more
core +2 more sources
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
BASE NACIONAL COMUM CURRICULAR - BNCC COMPONENTE CURRICULAR: GEOGRAFIA
Revista da ANPEGE, 2017 O artigo analisa a Base Nacional Comum Curricular (BNCC), tornada pública pelo Ministério da Educação em 2016. A Constituição Federal de 1988, construída nas mobilizações sindicais e sociais da década de 1980, estabeleceu a criação de conteúdos mínimos ...
Marcos Antonio Campos Couto
doaj +1 more source
AS DEMANDAS CONSERVADORAS DO MOVIMENTO ESCOLA SEM PARTIDO E A BASE NACIONAL CURRICULAR COMUM
, 2017 O artigo busca entender como a emergencia do movimento autodenominado Escola sem Partido e de suas demandas conservadoras deslocam as negociacoes politicas na elaboracao da base nacional curricular comum. O argumento central e que as negociacoes em curso
E. Macedo
semanticscholar +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Water quality for supplementary irrigation in the Quequén Salado river basin (Argentina) [PDF]
, 2004 This paper focuses on the study of the water quality in the courses which compose the Quequén Salado river basin, Argentina, in order to determine their suitability for supplementary irrigation.
Marini, Mario Fabián +1 more
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Educação (Santa Maria. Online), 2020 Este artigo pretende discutir as consequências da parceria entre o Ministério da Educação (MEC) e órgãos nacionais e internacionais que assumiram o papel de reguladores transnacionais de políticas de educação em diversos países, especialmente os ...
Rafael Rodrigo Mueller, André Cechinel
doaj +1 more source
A BASE NACIONAL COMUM CURRICULAR E A POLÍTICA NACIONAL DE ALFABETIZAÇÃO
Poiésis - Revista do Programa de Pós-Graduação em EducaçãoThe present study aimed to analyze the three editions of the Common National Curricular Base (BRASIL, 2015; 2016; 2017), the National Literacy Policy (BRASIL, 2019) and the (dis)articulation with contemporary policies in this area, in our country. This is a qualitative investigation (GIL, 2008; MINAYO, 2001), whose research techniques were based on ...
Ana Kátia Da Costa Silva +1 more
openaire +1 more source
Betalains and phenolic compounds of leaves and stems of Alternanthera brasiliana and Alternanthera tenella [PDF]
, 2018 Betacyanins and phenolic compounds from acetonitrile:acidified water extracts of Alternanthera brasiliana and Alternanthera tenella were characterized and quantified using a high-performance liquid chromatography system coupled with diode array and ...
Alvarez, I. +5 more
core +1 more source