BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Letramento Crítico na Base Nacional Comum Curricular:
Kiri-Kerê - Pesquisa em Ensino, 2022 O objetivo deste artigo é analisar três Competências Específicas que atravessam as habilidades preconizadas para o ensino-aprendizagem de Língua Portuguesa, a fim de verificar como os princípios do Letramento Crítico se revelam no documento normativo.
openaire +1 more source
Una revisión preliminar del estatus de conocimiento de los félidos argentinos [PDF]
, 2004 En Argentina ocurren 10 especies de félidos silvestres (el 28% del total mundial). A pesar de que el Grupo de Especialistas en Félidos de la UICN ha clasificado como bueno el estado de conservación de los felinos argentinos, esta categorización utilizó ...
Lucherini, Mauro +2 more
core
The proper motion of the Magellanic Clouds, I: first results and description of the program [PDF]
, 2009 We present the first results of a ground-based program to determine the proper motion of the Magellanic Clouds (MCs) relative to background quasars (QSO), being carried out using the Iréneé du Pont 2.5 m telescope at Las Campanas Observatory, Chile ...
Baume, Gustavo Luis +7 more
core +2 more sources
MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
FEBS Open Bio, EarlyView.During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
An approach to the Urgencies and Emergencies Medicine
Medisan, 2018 A study on the development of the Urgencies and Emergencies Medicine, its main concepts and peculiarities is carried out. The current pattern of the SIUM in Cuba is approached, which has been the solution to the severely-ill patient and it has allowed ...
Jorge Luis Sánchez Guillaume
doaj
Late Cambrian acritarchs from the Santa Rosita Formation: implications for the Cambrian-Ordovician boundary in the eastern Cordillera of northwest Argentina [PDF]
, 2003 Marine phytoplankton from the Late Cambrian are described for the first time in the Eastern Cordillera of northwest Argentina. The acritarch assemblage was recovered from an offshore lower mudstone unit towards the base of the Casa Colorada Member (Santa
Buatois, Luis Alberto +2 more
core
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source
Apreciação da base nacional comum curricular e a educação física em foco
Motrivivência, 2016 O presente artigo analisa o manuscrito da Base Nacional Comum Curricular e compreende a concepção de Educação Física por ele proposta. Identifica a concepção atribuída à educação física pela Base Nacional Comum Curricular.
Laine Rocha Moreira +4 more
doaj +1 more source