Results 31 to 40 of about 182,670 (299)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Single-Point Incremental Micro-Forming of Thin Shell Products Utilizing High Formability

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2010
This paper describes single-point incremental micro-forming of miniature shell products 50 µm to 1000 µm in size. First, the conditions of the micro-forming of a pyramid with a 1 mm square base were optimized to cause large elongation of a ...
Toshiyuki OBIKAWA   +5 more
doaj   +1 more source

A True Pyramid [PDF]

open access: yes, 2005
The term pyramid is used in two ways in logology: 1) a word pyramid is a word ladder in which each step adds a letter -eg, I IN FIN FIND FIEND FRIEND; 2) a pyramid word has an abstract \u27pyramid\u27 of letter frequencies -eg, REMEMBERER with 1B ...

core   +1 more source

Reconciling Contemporary Approaches to School Attendance and School Absenteeism: Toward Promotion and Nimble Response, Global Policy Review and Implementation, and Future Adaptability (Part 1) [PDF]

open access: yes, 2019
School attendance is an important foundational competency for children and adolescents, and school absenteeism has been linked to myriad short- and long-term negative consequences, even into adulthood.
Fornander, Mirae J.   +3 more
core   +5 more sources

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

Value supply chains at the base of the pyramid: studies of past and present textile networks [PDF]

open access: yesJournal of Humanitarian Logistics and Supply Chain Management, 2017
Purpose – Billions of entrepreneurs at the Base of the Pyramid (BoP) operate as small-scale producers within multi-tiered supply chain networks. Unfortunately, a majority of these entrepreneurs are simply unable to derive sufficient value from the ...
Sameer Prasad   +4 more
doaj   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela   +13 more
wiley   +1 more source

Consumption Characteristics Mapping of the Base of the Pyramid (BOP) Population in Brazil

open access: yesEmerging Markets Journal, 2015
The objective of this study is to outline a diagnosis of the BoP's population in Brazil, regarding their size and consumption characteristics. This is a relevant and current issue, considering that BoP needs to be understood as a large potential market ...
Renata Giovinazzo Spers   +1 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Consumption at the Bottom of the Pyramid: Current State of Research and Suggestions for Future Study

open access: yesEmerging Markets Journal, 2020
This article reviews the state of the literature on consumption at the bottom of the pyramid and summarizes the studies' suggestions for future research.
Alyce Cardoso Campos   +5 more
doaj   +1 more source

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