Results 101 to 110 of about 2,488,188 (299)
Molecular Oncology, EarlyView.The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens +8 more
wiley +1 more source
TABASCO: A single molecule, base-pair resolved gene expression simulator
BMC Bioinformatics, 2007 Background Experimental studies of gene expression have identified some of the individual molecular components and elementary reactions that comprise and control cellular behavior.
Endy Drew, Kelly Jason R, Kosuri Sriram
doaj +1 more source
Molecular Oncology, EarlyView.Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever +1 more
wiley +1 more source
On the Gelfand property for complex symmetric pairs [PDF]
, 2019 We first prove, for pairs consisting of a simply connected complex reductive group together with a connected subgroup, the equivalence between two different notions of Gelfand pairs. This partially answers a question posed by Gross, and allows us to use a criterion due to Aizenbud and Gourevitch, and based on Gelfand-Kazhdan's theorem, to study the ...
arxiv +1 more source
A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini +11 more
wiley +1 more source
iScience, 2022 Summary: Base pairs are fundamental building blocks of RNA. The base pairs of low stability are often critical in RNA functions. Here, we develop a solid-state NMR-based water-RNA exchange spectroscopy (WaterREXSY) to characterize RNA in solid.
Sha Zhao +10 more
doaj
Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors
Molecular Oncology, EarlyView.Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi +6 more
wiley +1 more source
Molecular Dynamics Simulation of Homo-DNA: The Role of Crystal Packing in Duplex Conformation
Crystals, 2019 The (4′→6′)-linked DNA homolog 2′,3′-dideoxy-β-D-glucopyranosyl nucleic acid (dideoxy-glucose nucleic acid or homo-DNA) exhibits stable self-pairing of the Watson−Crick and reverse-Hoogsteen types, but does not ...
Jonathan H. Sheehan +4 more
doaj +1 more source
Molecular Oncology, EarlyView.The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina +17 more
wiley +1 more source
Structural prediction of RNA switches using conditional base-pair probabilities.
PLoS ONE, 2019 An RNA switch triggers biological functions by toggling between two conformations. RNA switches include bacterial riboswitches, where ligand binding can stabilize a bound structure.
Amirhossein Manzourolajdad +1 more
doaj +1 more source