Results 151 to 160 of about 446,496 (303)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

An unnatural base pair for the detection of epigenetic cytosine modifications in DNA. [PDF]

Nat Chem
Schmidl D, Becker SM, Edgerton JM, Balasubramanian S.   +3 more
europepmc   +1 more source

emDNA - A Tool for Modeling Protein-decorated DNA Loops and Minicircles at the Base-pair Step Level. [PDF]

J Mol Biol, 2022
Young RT, Clauvelin N, Olson WK.
europepmc   +1 more source

The Effectiveness of Think Pair Share Learning Model with a Problem Based Learning Approach Based on Students’ Self-efficacy

, 2019
Ahmad Mukhibin, Nur Ichsan
openalex   +2 more sources

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Coconstruction of MOF/CNT-Based Interconnected Acid-Base Pair Hybrid Materials for Improved Performance in Proton Exchange Membranes. [PDF]

ACS Omega
Fu J, Wang J, Qu T, Liu H, Zhang Q, Gong C, Hu F.   +6 more
europepmc   +1 more source

Author Correction: Joint disease-specificity at the regulatory base-pair level. [PDF]

Nat Commun, 2022
Muthuirulan P, Zhao D, Young M, Richard D, Liu Z, Emami A, Portilla G, Hosseinzadeh S, Cao J, Maridas D, Sedlak M, Menghini D, Cheng L, Li L, Ding X, Ding Y, Rosen V, Kiapour AM, Capellini TD.   +18 more
europepmc   +1 more source

A method for estimating energy parameters of RNAs by differentiating base-pairing probabilities

Kazuhiko Yamamura, Goro Terai, Kiyoshi Asai   +2 more
openalex   +1 more source

Confronting two-pair primer design for enzyme-free SNP genotyping based on a genetic algorithm [PDF]

, 2010
Cheng‐Hong Yang, Yu‐Huei Cheng, Li‐Yeh Chuang, Hsueh‐Wei Chang   +3 more
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source