Results 211 to 220 of about 28,951,856 (408)

Regions containing repeating base-pairs in DNA from some oncogenic and nononcogenic animal viruses.

, 1967
H. Kubiński, J. A. Rose
openalex   +1 more source

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

Molecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren, Kathryn A. Wierenga, Frank M. Riemers, Elsbeth A. van Liere, Bart Westendorp   +4 more
wiley   +1 more source

Uniqueness of radiomic features in non‐small cell lung cancer

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose The uniqueness of radiomic features, combined with their reproducibility, determines the reliability of radiomic studies. This study is to test the hypothesis that radiomic features extracted from a defined region of interest (ROI) are unique to the underlying structure (e.g., tumor). Approach Two cohorts of non‐small cell lung cancer (
Gary Ge, Jie Zhang
wiley   +1 more source

Plc pairs with good asymptotic base loci [PDF]

arXiv
In this paper, we give a characterization of Fano type varieties of plc pairs. This extends a result due to Choi and Park for pklt pairs. Moreover, we show that for a plc pair $(X,\Delta)$, if no plc centers are contained in the augmented base locus $\mathbf{B}_{+}(-(K_X+\Delta))$, then $(X,\Delta)$ admits a good $-(K_X+\Delta)$-minimal model.
arxiv  

G.T wobble base-pairing in Z-DNA at 1.0 A atomic resolution: the crystal structure of d(CGCGTG). [PDF]

, 1985
P Shing Ho, Claire Frederick, Gary J. Quigley, G. A. VAN DER MAREL, Jacques H. van Boom, A.H. Wang, Alexander Rich   +6 more
openalex   +1 more source

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

Molecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh, Amelia Martinez Villarreal, Philippe Lefrançois, Jennifer Gantchev, Sriraam Sivachandran, Samy Abou Setah, Ivan V. Litvinov   +6 more
wiley   +1 more source

A small footprint couch‐top support device for image‐guided radiotherapy of heavy patients

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose Patients with body weights close to or above 400 lbs present unique challenges in radiation therapy since the weight limit of most treatment couches decreases as the couch‐top extends toward the treatment gantry. The purpose of this work was to develop a small footprint couch‐top support platform to safely perform image‐guided ...
Huixiao Chen, Kevin Morley, Ronnie Rodriguez, Emily Draeger, Muhammad Shafiq ul Hassan, Zhe (Jay) Chen   +5 more
wiley   +1 more source

Structural analysis of base mispairing in DNA containing oxidative guanine lesion

Open Physics, 2007
Fujimoto Hirofumi, Pinak Miroslav, Nemoto Toshiyuki, Bunta Juraj   +3 more
doaj   +1 more source

RNAStructViz: graphical base pairing analysis. [PDF]

Bioinformatics, 2021
Schmidt MD, Kirkpatrick A, Heitsch C.
europepmc   +1 more source

Sequence specificity of mutagen-nucleic acid complexes in solution: Intercalation and mutagen-base pair overlap geometries for proflavine binding to dC-dC-dG-dG and dG-dG-dC-dC self-complementary duplexes

, 1977
Dinshaw J. Patel, Lita L. Canuel
openalex   +1 more source