Results 251 to 260 of about 965,609 (309)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Interplay of the ribosome A and CAR sites. [PDF]

NAR Genom Bioinform
Raval M, Zhou Y, Lynch M, Krizanc D, Thayer KM, Weir MP.   +5 more
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Extreme GC3 codon bias in a novel brown seaweed virus results in pseudoambigrammatic characteristics. [PDF]

Virus Evol
Dekker RJ, de Leeuw WC, Rauwerda H, van Olst MF, Ensink WA, van Leeuwen SM, Cohen J, Timmermans K, Breit TM, Jonker MJ.   +9 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Transfer learning for T-cell response prediction. [PDF]

BMC Bioinformatics
Stadelmaier J, Malone B, Eggeling R.
europepmc   +1 more source

Synthetic short RNA in cancer. [PDF]

Front Oncol
Tomita T, Minagawa K, Hiratsuka S.
europepmc   +1 more source

NuConf: a rotamer library for DNA and RNA and its implementation in the protein design software MUMBO. [PDF]

Sci Rep
Makarova MO, Stiebritz MT, Basturk D, Lemke B, Süss B, Muller YA.   +5 more
europepmc   +1 more source

Activation of Oligonucleotide Polyanions Using Collisions, Electrons and Photons in a timsOmni Platform. [PDF]

J Am Soc Mass Spectrom
Rosu F, Chiba R, Mallika AM, Smyrnakis A, Greisch JF, Papanastasiou D, Gabelica V.   +6 more
europepmc   +1 more source