Results 131 to 140 of about 8,322,522 (296)

Temperatura base para abertura de floretes e antocrono em gladíolo

Revista Ceres
RESUMO O gladíolo é uma flor de corte de grande importância nos mercados nacional e mundial. A haste floral, do tipo espiga, é composta por floretes que apresentam abertura acropetal. O conhecimento da velocidade de abertura desses floretes, representada
Natalia Teixeira Schwab, Nereu Augusto Streck, Lilian Osmari Uhlmann, Bruna San Martin Rolin Ribeiro, Camila Coelho Becker, Josana Andreia Langner   +5 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Leaf expansion and leaf turnover of perennial C4 grasses growing at moderately low temperatures

Revista de la Facultad de Ciencias Agrarias, 2017
Understanding the mechanisms by which some C4 grasses grow more than others at moderately low temperatures (~12-20ºC) is valuable to select materials to lengthen the growing season.
Germán D. Berone
doaj  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Estimating Cardinal Temperatures and Effect of Different Levels of Temperature on Germination Indices of Redstem Filaree (Erodium cicutarium)

پژوهش‌های بذر ایران, 2016
In order to study the responses of redstem filaree (Erodium cicutarium L.) seed germination to temperature levels, an experiment was carried out in a completely randomized design with four replications and twelve levels of temperature (0, 3, 5, 7, 10, 12,
Marjan Diyanat, Seyyed Meisam Hosseini
doaj  

Spatial Variations in Seed Germination Traits of White Spruce (Picea glauca) and Black Spruce (P. mariana) Across the Canadian Boreal Forest

Plants
This study focuses on the spatial variation in seed germination characteristics of Picea glauca and P. mariana, prominent and widespread species within the Canadian boreal forest.
Elaine Qualtiere, Yongsheng Wei, Dustin Snider, Yuguang Bai, Mark Johnston, Daniel W. McKenney, Pia Papadopol, Dale Simpson   +7 more
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Modelling and Validation of Computer Vision Techniques to Assess Heart Rate, Eye Temperature, Ear-Base Temperature and Respiration Rate in Cattle. [PDF]

Animals (Basel), 2019
Jorquera-Chavez M, Fuentes S, Dunshea FR, Warner RD, Poblete T, Jongman EC.   +5 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source