Results 31 to 40 of about 836,425 (219)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Germination Parameters of Selected Summer Weeds: Transferring of the AlertInf Model to Other Geographical Regions

Agronomy, 2021
Effective weed management depends on correct control timing, which depends on seedling emergence dynamics. Since soil temperature and soil moisture are the two main factors that determine weed germination, the hydrothermal time model can be used to ...
Valentina Šoštarčić, Roberta Masin, Donato Loddo, Ema Brijačak, Maja Šćepanović   +4 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Using thermal time to predict the timing of flight activity in Noctuidae (Lepidoptera) species: Calculation and verification of forecast methods

Plant Protection Science
From 1967 to 1995, the flight activity of 25 monovoltine species of moths (Noctuidae, Lepidoptera) was monitored via a light trap located in Prague (50.09 N, 14.30 E).
Alois Honěk, Zdenka Martinková, Ivo Novák, Terezia Jauschová, Lenka Sarvašová, Miroslav Saniga, Milada Holecová, Ján Kulfan, Peter Zach   +8 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Evaluation of germination characteristics and determination of cardinal temperatures of poppy (Papaver somniferum) seed [PDF]

علوم و فناوری بذر ایران, 2017
The aim of this study was to quantify the response of germination rate to temperature and to find cardinal temperatures required for different germination percentiles in Papaver somniferum. Four models of non-linear regression [Quadratic, Segmented, Beta
V. Amiri Monfared, A. Hashemi, A. Mamedi, R. Tavakkol Afshari   +3 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Performance Analysis of Short-Term Electricity Demand with Atmospheric Variables

Energies, 2018
The quality of short-term electricity demand forecasting is essential for the energy market players for operation and trading activities. Electricity demand is significantly affected by non-linear factors, such as climatic conditions, calendar components
Kamal Chapagain, Somsak Kittipiyakul
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

The effect of the triangular rib usage in the plate fin heat sinks on the pressure drop, base plate temperature, and entropy generation

European Mechanical Science, 2023
Improving the thermal efficiency in plate fin heat sinks (PFHS) results in a reduction in the weight, volume and cost of the heat sink. This ensures long life and reliable operation of the cooled equipment.
Muhammet Nasıf Kuru
doaj   +1 more source