Results 61 to 70 of about 4,685,493 (256)

Leukemia and Exposure to Potential Benzene Sources in Children From the Mexico City Metropolitan Area, 2010–2021: A Geospatial Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Leukemia is the most common childhood cancer in Mexico, and acute lymphoblastic leukemia (ALL) is the most frequent subtype. Exposure to high concentrations of benzene has been associated with ALL incidence, particularly in urban areas. This study evaluated the relationship between distance to benzene emission sources and the number
Orlando Rivera Zurita, Norma Candelaria López Santiago, Claudia Maria García Cuellar, Karla Maldonado Silva, Nancy Reynoso Noverón, Leticia Hernández Cadena   +5 more
wiley   +1 more source

Application of patient-reported outcomes in clinical trials of traditional Chinese medicine registered in international clinical trials registry platform, from 2010 to 2022: a cross-sectional study

Journal of Patient-Reported Outcomes
Purpose Patient-reported outcomes (PROs) assist patients and clinicians in assessing treatment effectiveness and enhancing healthcare quality. This study aims to explore and analyze the application and characteristics of PROs in clinical trials of ...
Yuanyuan Lin, Xiaowen Zhang, Zhenqian Xu, Lin Liu, Chen Shen, Mei Han, Huijuan Cao, Yutong Fei, Jianping Liu, Hongguo Rong, Chunxia Zhou   +10 more
doaj   +1 more source

Oral and injectable Marsdenia tenacissima extract (MTE) as adjuvant therapy to chemotherapy for gastric cancer: a systematic review

BMC Complementary and Alternative Medicine, 2019
Background Marsdenia tenacissima extract (MTE) is a phytochemical widely used as complementary therapy in cancer care. This systematic review was conducted to investigate the anticancer and detoxification effects of MTE, as an adjuvant therapy to ...
Xu Zhou, Meilu Liu, Qing Ren, Weifeng Zhu, Yang Wang, Haochen Chen, Jianrong Chen   +6 more
doaj   +1 more source

Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte, Hannah Koch, Olivia A. Coughlin, Jillian R. Bouck, Allie Carter, Seethal A. Jacob   +5 more
wiley   +1 more source

Evidence-Based Medicine [PDF]

Pediatrics, 2000
To the Editor. Regarding Dr Bauchner's comments in an article published in your journal,1 I was struck by the author's concern that evidence-based medicine (EBM) “may be distracting from the important goal of finding ways to change physician behavior.” Dr Bauchner discussed in a nice overview the rigors of the statistical methods incorporated in the ...
openaire   +4 more sources

Psychosocial Functioning After Pediatric Bone Sarcoma: Generic and Survivor‐Specific Outcomes in Adolescent and Young Adult Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric bone sarcoma patients and survivors may experience psychosocial challenges related to childhood cancer after their intensive, body‐altering treatment. This cross‐sectional study aimed to evaluate generic and survivor‐specific psychosocial outcomes in a national cohort of pediatric bone sarcoma patients and survivors, and ...
Hinke van der Hoek, Heleen Maurice‐Stam, Laura R. Beek, Jennifer van Dijk, Marjolein E. M. Langemeijer, Relinde W. Slooff‐Lentink, Alied M. van der Aa‐van Delden, Anne Westerweel, Marloes van Gorp, Hendrik W. B. Schreuder, Lianne M. Haveman, W. Peter Bekkering, Leonie G. Tigelaar, Johannes H. M. Merks, Martha A. Grootenhuis   +14 more
wiley   +1 more source

Identifying, handling and impact of immortal time bias on addressing treatment effects in observational studies using routinely collected data

BMC Medical Research Methodology
Background Immortal time bias (ITB) represents a methodological challenge in evaluating treatment effects in observational studies using routinely collected data (RCD).
Shuangyi Xie, Jiayue Xu, Qiao He, Yuning Wang, Qianrui Li, Xia Zhang, Yunxiang Huang, Yuanjin Zhang, Wen Wang, Xin Sun   +9 more
doaj   +1 more source

Methodological quality (risk of bias) assessment tools for primary and secondary medical studies: what are they and which is better?

Military Medical Research, 2020
Methodological quality (risk of bias) assessment is an important step before study initiation usage. Therefore, accurately judging study type is the first priority, and the choosing proper tool is also important.
Lin-Lu Ma, Yun-Yun Wang, Zhi-Hua Yang, Di Huang, Hong Weng, Xian-Tao Zeng   +5 more
doaj   +1 more source

Ironic Medications: A Narrative‐Based Psycho‐Educational Intervention to Explore Patient–Provider Communication in Adolescents With Haematological Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adolescents with haematological malignancies face significant emotional and relational challenges, often accompanied by difficulties in communicating their needs within the healthcare context. To address these issues, a narrative‐based psycho‐educational intervention based on the creation and prescription of Ironic Medications was ...
Marta Stoppa, Elena Pagani Bagliacca, Selena Russo, Giulia Rampoldi, Maria Grazia Strepparava, Adriana Cristina Balduzzi, Andrea Biondi, Marco Spinelli   +7 more
wiley   +1 more source

Efficacy and safety of thiazolidinediones in diabetes patients with renal impairment: a systematic review and meta-analysis

Scientific Reports, 2017
We conducted a systematic review and meta-analysis to evaluate the efficacy and safety of TZDs in treatment of diabetes mellitus patients with renal impairment. We searched PubMed, EMBASE and Cochrane Central Register of Controlled Trials.
Wen Wang, Xu Zhou, Joey S. W. Kwong, Ling Li, Youping Li, Xin Sun   +5 more
doaj   +1 more source