Results 161 to 170 of about 837,725 (254)

Long‐term outcomes of microsurgical interdental papilla reconstruction: 13‐year and 18‐year case follow‐ups

open access: yesClinical Advances in Periodontics, EarlyView.
Abstract Background Loss of the interdental papilla compromises esthetics, speech, and hygiene, significantly affecting quality of life and psychological well‐being. Reconstruction has long been considered unpredictable, particularly in Cairo RT3 cases with advanced interproximal bone loss.
Katsuhiko Akiyama
wiley   +1 more source

Ten‐year follow‐up of bilateral gingival recession treatment: A case report

open access: yesClinical Advances in Periodontics, EarlyView.
Abstract Background This work aims to present a 10‐year follow‐up of a young patient who underwent treatment with collagen matrix (CM) combined with enamel matrix derivative (EMD) for bilateral gingival recessions in the maxillary canine region. Methods The patient, a 25‐year‐old woman, presented with bilateral Cairo type 1 recessions.
Luiz C. L. Marques‐Junior   +4 more
wiley   +1 more source

A Unified Approach for the Synthesis of Conformationally Locked and sp2‐sp3 Fused Hybrids

open access: yesChemistry – A European Journal, EarlyView.
This study presents a systematic platform to build rigid sp2–sp3 hybrids via benzyne cycloadditions. Arene‑fused bicyclic oxa‐, aza‐, and carbocycles are converted into medicinally relevant amino acids and applied to Enalapril analogues synthesis. The hybrids combine aromatic interactions with 3D rigidity, tuning lipophilicity, pKa, and solubility ...
Ervis Saraci   +8 more
wiley   +1 more source

Digital Transformation of Medicines Regulation in Africa—Perspectives from a Stakeholder Convening

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Regulatory authorities worldwide are developing strategies to integrate artificial intelligence (AI) into the lifecycle of health products, technologies, and medicines. While regulators share goals of improving efficiency, strengthening decision‐making, and protecting public health, their approaches differ according to institutional structures ...
Christelna Reyneke   +12 more
wiley   +1 more source

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