Results 41 to 50 of about 837,725 (254)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Basel Problem – Preliminaries [PDF]

open access: yesFormalized Mathematics, 2017
Summary In the article we formalize in the Mizar system [4] preliminary facts needed to prove the Basel problem [7, 1]. Facts that are independent from the notion of structure are included here.
Artur Kornilowicz, Karol Pak
openaire   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

ANALYSIS OF NEW RECOMMENDATIONS OF BASEL COMMITTEE ON BANKING SUPERVISION

open access: yesRussian Journal of Economics and Law, 2013
Objective: determining and analyzing differences between the old and new recommendations of Basel committee on banking supervision. Methods: abstract-logical.
D. S. Mel’Nik
doaj  

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller   +14 more
wiley   +1 more source

Současný a budoucí vývoj českého bankovnictví z pohledu regulace EU zaměřené na kapitálovou přiměřenost [PDF]

open access: yesACC Journal, 2012
Článek pojednává o současném a budoucím vývoji českého bankovního sektoru z hlediska regulace EU zaměřené na kapitálovou přiměřenost. Úvodní část práce popisuje rozdíly v regulaci bankovnictví, a to zejména mezi Basel II a novým regulatorním rámcem Basel
Andrea Kobík Valihorová
doaj  

Technology Transfer at the University of Basel

open access: yesCHIMIA, 2004
The University of Basel is Switzerland's oldest university. Since 1996 the University has enjoyed an 'autonomous status' and is governed by a 'University Council'.
Bruno H. Dalle Carbonare
doaj   +1 more source

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