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International Banking Regulation: Developments from Basel I to the 2017 Final Reforms

Encyclopedia
The Basel Accords refer to a series of international banking regulatory frameworks developed by the Basel Committee on Banking Supervision to strengthen the stability and resilience of the global banking system. Introduced as Basel I, Basel II, and Basel
Shitnaan Wapmuk, Mark Ching-Pong Poo, Yui-yip Lau   +2 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Basilea II: panacea o opportunità mancata? (Basel II: Panacea or a Missed Opportunity? )

Moneta e Credito, 2012
At end-June 2004, the Basel Committee on Banking Supervision finally issued the "New Capital Accord" ("Basel II"), following endorsement by G10 bank supervisors.
Maximilian J.B. Hall
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

SME’S Rating System and Process in Turkey According to the Basel II Settlements [PDF]

Eurasian Journal of Business and Economics, 2009
Basel II settlements have a strong influence on the SMEs that are of great importance to countries’ economies. Conditions to become an SME have changed and rating of SMEs has become very important with this new settlement.
Sinan ASLAN, Hatice ELÇİ
doaj  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

MARKET REACTION TO THE IMPLEMENTATION OF BASEL CAPITAL IN SOUTH AFRICAN BANKS: EVENT STUDY APPROACH

The International Journal of Banking and Finance
This study investigated the stock market reaction and the effect of the implementation of Basel II and Basel III on the stock returns of South African banks.
Damilola Oyetade, Paul-Francois Muzindutsi   +1 more
doaj   +1 more source

Did Bank Capital Regulation Exacerbate the Subprime Mortgage Crisis?

Discrete Dynamics in Nature and Society, 2009
This contribution is the second in a series of papers on discrete-time modeling of bank capital regulation and its connection with the subprime mortgage crisis (SMC). The latter was caused by, amongst other things, the downturn in the U.S. housing market,
M. A. Petersen, M. C. Senosi, J. Mukuddem-Petersen, M. P. Mulaudzi, I. M. Schoeman   +4 more
doaj   +1 more source

The Impact of Changes in Basel Capital Requirements on the Resilience of African Commercial Banks

Scientific Annals of Economics and Business, 2022
Focusing on a panel sample of 41 commercial banks over the period of 2000-2018, this study examined the effect of capital adequacy on the resilience of commercial banks in Africa under changing Basel levels (II, III, and the proposed Basel IV). The study
Damilola Oyetade, Adefemi A. Obalade, Paul-Francois Muzindutsi   +2 more
doaj   +1 more source