Results 41 to 50 of about 337,814 (260)

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

MARKET REACTION TO THE IMPLEMENTATION OF BASEL CAPITAL IN SOUTH AFRICAN BANKS: EVENT STUDY APPROACH

open access: yesThe International Journal of Banking and Finance
This study investigated the stock market reaction and the effect of the implementation of Basel II and Basel III on the stock returns of South African banks.
Damilola Oyetade   +1 more
doaj   +1 more source

SME’S Rating System and Process in Turkey According to the Basel II Settlements [PDF]

open access: yesEurasian Journal of Business and Economics, 2009
Basel II settlements have a strong influence on the SMEs that are of great importance to countries’ economies. Conditions to become an SME have changed and rating of SMEs has become very important with this new settlement.
Sinan ASLAN, Hatice ELÇİ
doaj  

The effect of stressed economic conditions on credit risk in Basel II

open access: yesSouth African Journal of Economic and Management Sciences, 2011
The robustness of the Basel II accord in protecting banks during volatile economic periods has been challenged in the ongoing credit crisis. In particular, advanced approaches to measuring and managing credit risk have drawn criticism for being both ...
Ja'nel Esterhuysen   +2 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Basel II öncesi ve sonrası dönemde sermaye yeterliliğinin Türk mevduat bankalarının kârlılığı üzerindeki etkisi

open access: yesAfyon Kocatepe Üniversitesi İktisadi ve İdari Bilimler Fakültesi Dergisi, 2022
Bu çalışmanın amacı Türk mevduat bankalarının sermaye yeterliliğinin aktif kârlılıkları (ROA) üzerindeki etkisini analiz etmektir. Bu amaçla, 2007Q4-2020Q3 dönemine ilişkin üçer aylık veriler kullanılarak panel veri regresyon analizi gerçekleştirilmiştir.
Adalet Hazar   +2 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Risk management debate focused on banking industry

open access: yesInternational Journal of Entrepreneurial Knowledge, 2013
Corporate governance is a subject of constant timeliness and broad interest, mainly aimed at ensuring adequate protection for investors and financial institutions.
Eugenia Ana Matis   +2 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

BASEL II DÜZENLEMESİ VE TÜRKİYE'YE ETKİLERİ

open access: yesSelçuk Üniversitesi Sosyal Bilimler Meslek Yüksekokulu Dergisi, 2014
Basel Komitesi uluslararası finans piyasaları için yayınladığı BaselII düzenlemesini 2001 yılında yayınlayıp, tanıttı. Gelen yorum ve görüşlerden sonra en son hali 2004 yılında yayımlandı.
Baki Yılmaz, Mutlu Cerit
doaj  

Home - About - Disclaimer - Privacy