Results 31 to 40 of about 239,330 (291)
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
BASEL III CAPITAL ADEQUACY REQUIREMENTS AND THEIR EFFECTS ON THE TURKISH BANKING SYSTEM
Journal of Business Administration and Social Studies, 2021 The banking system capital and liquidity shortage formed after the global mortgage crisis of 2007 and the European crisis of 2009 has emerged as a major threat to the global economy.
Gulrukh GASIMOVA, Azar KARIMOV
doaj
Transformation of the Ukrainian banking system regulation: a new horizon of compliance with the international framework [PDF]
Banks and Bank Systems, 2019 This article discusses the latest methodological recommendations of the Basel Committee on Banking Supervision developed in response to the effects of the global financial crisis and known as Basel III.
Lyubov Khudoliy, Oleg Bronin
doaj +1 more source
Basel III: is the cure worse than the disease?
, 2012 This paper discusses the economic impact of the Basel III reforms to banking regulation. We find that the long-term impact should be much less than many in the industry fear but the required accompanying changes to business models, business processes and
Milne, A. +3 more
core +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Towards a New Basel Accord with More Rigorous Settlements [PDF]
Theoretical and Applied Economics, 2010 The recent financial crisis made the banking sector more vulnerable to shocks. The system was characterised by weaknesses: too much leverage in the banking; not enough high quality capital to absorb losses and excessive credit growth based on ...
Petru PRUNEA, Daniela COSMA
doaj +1 more source
Selçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2016 KOBİ’ler için Uluslararası Finansal Raporlama Standartları KOBİ UFRS ve Basel III Kriterleri, KOBİ’leri yakından ilgilendiren iki önemli düzenlemedir.
Tuğrul Kandemir, Arif Arifoğlu
doaj
Jurnal ASET (Akuntansi Riset), 2019 Abastract. Legitimacy theory has a big role in strengthening the function of banks as intermediaries. This study aims to analyze bank compliance in lending in accordance with the provisions of the Basel Accord I - III. Based on the results of an analysis
Dadang Agus Suryanto
doaj +1 more source