Results 141 to 150 of about 348,770 (326)

Shifting baselines and social license to operate: Challenges in communicating sea lamprey control

, 2021
Marc Gaden, Cory O. Brant, Richard C. Stedman, Steven J. Cooke, Nathan Young, T. Bruce Lauber, Vivian M. Nguyen, Nancy A. Connelly, Barbara A. Knuth   +8 more
openalex   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Climate Change and Economic Growth: Impacts and Interactions [PDF]

An integrated assessment model (ENVISAGE), including a CGE-based economic module and a climate module, is used to assess the effects of a variety of economic impacts induced by climate change.
Dominique van der Mensbrugghe
core  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Leveraging the genetic diversity of trout in the rivers of the British Isles and northern France to understand the movements of sea trout (Salmo trutta L.) around the English Channel

Evolutionary Applications
Populations of anadromous brown trout, also known as sea trout, have suffered recent marked declines in abundance due to multiple factors, including climate change and human activities.
R. Andrew King, Charlie D. Ellis, Dorte Bekkevold, Dennis Ensing, Thomas Lecointre, Daniel R. Osmond, Adam Piper, Dylan E. Roberts, Sophie Launey, Jamie R. Stevens   +9 more
doaj   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Deep graph neural networks for spatiotemporal forecasting of sub-seasonal sea ice: A case study in Hudson Bay

Applied Ocean Research
This study introduces GraphSIFNet (Graph Sea Ice Forecast neural Network), a novel graph-based deep learning framework for spatiotemporal sea ice forecasting.
Zacharie Gousseau, Philippe Lamontagne, Mohammad Sina Jahangir, K. Andrea Scott   +3 more
doaj   +1 more source

The Late Pleistocene mollusk fauna of Selitrennoye (Astrakhan province, Russia): A natural baseline for endemic Caspian Sea faunas

, 2019
Sabrina van de Velde, Т.А. Yanina, Thomas A. Neubauer, Frank P. Wesselingh   +3 more
openalex   +1 more source

Checklist of amphipods of italian seas: baseline for monitoring biodiversity

This preliminary study presents an updated checklist of amphipod crustaceans inhabiting Italian seas and provides valuable insights into their diversity, distribution, and ecological traits. By combining existing literature with unpublished data, we were able to record 500 species in Italian waters.
Antonina Badalucco, Rocco Auriemma, Andrea Bonifazi, Roberta Cimmaruta, Elvira De Matthaeis, Cristina Gioia Di Camillo, Valentina Esposito, Davide Jacofano, Traudl Krapp, Leonardo Latella, Loretta Lattanzi, Marco Lezzi, Monica Lionello, Emanuele Mancini, Agnese Marchini, Veronica Marusso, Ermelinda Prato, Felicita Scapini, Maria Beatrice Scipione, Monica Targusi, Francesco Tiralongo, Benedetta Trabucco, Alberto Ugolini, Sabrina Lo Brutto   +23 more
openaire   +2 more sources