Results 151 to 160 of about 348,770 (326)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Co-located wave and offshore wind farms: A preliminary approach to the shadow effect [PDF]
, 2014 In recent years, with the consolidation of offshore wind technology and the progress carried out for wave energy technology, the option of combine both technologies has arisen.
Abanades, J +4 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Haematologic and plasma biochemical reference intervals for flatback turtles Natator depressus
Endangered Species ResearchBlood reference intervals (RIs) provide an indication of systemic health and are central to any baseline health survey. RIs are available for all sea turtle species, except for the flatback turtle Natator depressus.
EJ Young +8 more
doaj +1 more source
Summary of Coral Cay Conservation's habitat mapping data from Utila, Honduras [PDF]
, 2002 IIThe coral reefs of Honduras are of vital national and international importance,both ecologically and economically, but are threatened because of rapid economicand population growth.?
Afzal, D +4 more
core
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
The Governance of the SEA in the 2007-2013 EU Programs: the case of Italy [PDF]
The Governance of the SEA in the 2007-2013 EU Programs: the case of Italy The European Union 2007-2013 funds programming is a relevant frame in order to analyse the implementation of Strategic Environment Assessment (SEA) of plans and programs.
Andrea Forni +4 more
core
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source