Results 201 to 210 of about 153,280 (261)

Imaging the Tumor Microenvironment Beyond Anatomy: Functional, Immune, Stromal, and Metabolic Signatures for Precision Oncology

open access: yesiRADIOLOGY, EarlyView.
This article highlights the importance of imaging the tumor microenvironment (TME) beyond conventional anatomy‐based approaches to enable more precise oncology. It focuses on capturing key biological dimensions of tumors—vascular function and hypoxia, immune response, stromal remodeling, and metabolic activity—using advanced imaging techniques.
Karthikeyan Elumalai   +1 more
wiley   +1 more source

Construction and validation of a prognostic model for colorectal cancer based on bioinformatics and basement membrane-related genes. [PDF]

open access: yesEur J Med Res
Wei J   +11 more
europepmc   +1 more source

Redox‐Associated Renal and Male Reproductive Alterations Following Dexamethasone Exposure in Male Rats: Histopathological and Spermatological Evaluations

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Dexamethasone (DEX) is widely used in clinical practice, although it may also cause oxidative stress–related damage in different tissues, including the kidney and male reproductive system. This study investigated DEX‐induced renal and reproductive injury in rats and evaluated the modulatory effect of reduced glutathione on DEX‐associated redox
Caner Öztürk   +4 more
wiley   +1 more source

Epigenetically Regulated NOX4/NRF2 Axis Mediates PM2.5‐Induced Ferroptosis and Inflammatory Response in Membranous Nephropathy

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT This study aims to explore the involvement and mechanism of ferroptosis in particulate matter 2.5 (PM2.5)–induced membranous nephropathy (MN) progression. A cationic bovine serum albumin (cBSA)–induced mouse model of MN was established, followed by PM2.5 exposure.
Yanhong Gao   +8 more
wiley   +1 more source

Dasatinib and quercetin prevent alveolar bone loss in aged mice

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Recent findings have associated alveolar bone loss (ABL) with the presence of senescent cells. Aging and the accumulation of senescent cells are associated with a pro‐inflammatory environment which may exacerbate tissue damage.
Luisa S. Battistelli   +7 more
wiley   +1 more source

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