Complexities of the glomerular basement membrane [PDF]
Nature Reviews Nephrology, 2020 The glomerular basement membrane (GBM) is a key component of the glomerular capillary wall and is essential for kidney filtration. The major components of the GBM include laminins, type IV collagen, nidogens and heparan sulfate proteoglycans. In addition, the GBM harbours a number of other structural and regulatory components and provides a reservoir ...
Mychel Raony Paiva Teixeira Morais +2 more
exaly +3 more sources
Complement in anti-glomerular basement membrane glomerulonephritis [PDF]
Frontiers in ImmunologyAnti-glomerular basement membrane glomerulonephritis (anti-GBM GN) is a rare autoimmune disease that often progresses to end-stage renal disease (ESRD).
Pei Zhang +5 more
doaj +2 more sources
A rare case of sero-negative anti-glomerular basement membrane disease combined with diabetic nephropathy and literature review [PDF]
Renal FailureWe report a case of a 59-year-old male who exhibited an insidious onset of hematuria, nephrotic syndrome, and mild renal dysfunction, with negative serum anti-glomerular basement membrane antibodies.
Wenbo Wang +6 more
doaj +2 more sources
Anti-glomerular basement membrane disease superimposed on membranous nephropathy after coronavirus disease 2019: A case report [PDF]
Journal of International Medical ResearchMembranous nephropathy concurrent with anti-glomerular basement membrane disease is rarely reported. Acute kidney injury is prominent when these diseases coexist. Coronavirus disease 2019 may trigger this superimposition.
Rongrong Hu +6 more
doaj +2 more sources
Multiple occurrences of membranous nephropathy complicated with anti-glomerular basement membrane antibody and anti-neutrophil cytoplasm antibody double-negative crescentic formation since the COVID-19 pandemic: A case series [PDF]
Journal of International Medical ResearchThere has been an unusual increase in the incidence of anti-glomerular basement membrane disease, anti-neutrophil cytoplasm antibody (ANCA)-associated vasculitis, and double-positive cases since the coronavirus disease 2019 (COVID-19) pandemic.
Shuang Yuan +5 more
doaj +2 more sources
Atypical Anti–Glomerular Basement Membrane Disease [PDF]
Kidney International ReportsLoreto Fernández-Lorente +14 more
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Protein A immunoadsorption for anti-glomerular basement membrane nephritis [PDF]
HeliyonAnti-glomerular basement membrane (GBM) nephritis is a rare autoimmune disorder characterized by acute and rapidly progressive glomerulonephritis. In this report, we present the case of a 52-year-old woman with anti-GBM nephritis who was treated with ...
Caihong Liu +4 more
doaj +2 more sources
The glomerular basement membrane [PDF]
Experimental Cell Research, 2012 The kidney's glomerular filtration barrier consists of two cells-podocytes and endothelial cells-and the glomerular basement membrane (GBM), a specialized extracellular matrix that lies between them. Like all basement membranes, the GBM consists mainly of laminin, type IV collagen, nidogen, and heparan sulfate proteoglycan.
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Anti-Glomerular Basement Membrane Disease in a 10-year-old Child: A Case Report
Journal of Nepal Medical Association, 2023 Anti-glomerular basement membrane disease is an extremely uncommon entity in children. It has an incidence of 0.5 to 1 per million per year in adults and is even more uncommon in children.
Md Firoz Anjum +4 more
doaj +1 more source
Anti-GBM disease with positive serum anti-GBM antibodies but negative IgG deposition: A case report
SAGE Open Medical Case Reports, 2023 Anti-glomerular basement membrane antibodies are significantly specific for detecting anti-glomerular basement membrane disease. These antibodies are typically targeted against the non-collagenous (NC1) domain of the alpha 3 chain of type IV collagen and,
Kimia Kazemzadeh +3 more
doaj +1 more source