Results 21 to 30 of about 36,211 (244)
Atypical Anti–Glomerular Basement Membrane Disease [PDF]
Loreto Fernández-Lorente +14 more
doaj +2 more sources
Anti-Glomerular Basement Membrane Disease in Association with Pembrolizumab Treated with Rituximab in Addition to Standard Care: A Case Report. [PDF]
Introduction: Immune checkpoint inhibitors have significantly improved the prognosis of patients with certain malignancies; however, they can also be associated with diverse autoimmune organ toxicities, including those affecting the kidney.
Lopez T, Srikantharajah M, McAdoo S.
europepmc +2 more sources
Glomerular basement membrane as a compressible ultrafilter
The ultrafiltration properties of isolated glomerular basement membrane were studied in vitro by forming membrane fragments into thin films for use as ultrafiltration membranes. The filtration properties of the films were examined using cytochrome c, myoglobin, lysozyme, ovalbumin, lactoglobulin, and serum albumin.
Robinson, G B, Walton, H A
openaire +4 more sources
Protein A immunoadsorption for anti-glomerular basement membrane nephritis [PDF]
Anti-glomerular basement membrane (GBM) nephritis is a rare autoimmune disorder characterized by acute and rapidly progressive glomerulonephritis. In this report, we present the case of a 52-year-old woman with anti-GBM nephritis who was treated with ...
Caihong Liu +4 more
doaj +2 more sources
The glomerular basement membrane [PDF]
The kidney's glomerular filtration barrier consists of two cells-podocytes and endothelial cells-and the glomerular basement membrane (GBM), a specialized extracellular matrix that lies between them. Like all basement membranes, the GBM consists mainly of laminin, type IV collagen, nidogen, and heparan sulfate proteoglycan.
+6 more sources
Anti-GBM disease with positive serum anti-GBM antibodies but negative IgG deposition: A case report
Anti-glomerular basement membrane antibodies are significantly specific for detecting anti-glomerular basement membrane disease. These antibodies are typically targeted against the non-collagenous (NC1) domain of the alpha 3 chain of type IV collagen and,
Kimia Kazemzadeh +3 more
doaj +1 more source
Alport syndrome results from a myriad of variants in the COL4A3, COL4A4, or COL4A5 genes that encode type IV (basement membrane) collagens. Unlike type IV collagen α1(IV)2α2(IV)1 heterotrimers, which are ubiquitous in basement membranes, α3/α4/α5 have a ...
Dominic Cosgrove, Jacob Madison
doaj +1 more source
Glomerular basement membrane and related glomerular disease [PDF]
The glomerular basement membrane (GBM) is lined by fenestrated endothelium from the capillary-lumen side and by interdigitating foot processes of the podocytes from the urinary- space side. These three layers of the glomerular capillary wall constitute the functional unit of the glomerular filtration barrier.
Ying Maggie, Chen, Jeffrey H, Miner
openaire +2 more sources
Tubular basement membrane deposits after allogeneic hematopoietic stem cell transplantation
Background Extraglomerular immune complex deposition is rare and only a few membranous nephropathy cases with tubular basement membrane deposits have been reported following allogeneic hematopoietic stem cell transplantation.
Wenyan Zhou +4 more
doaj +1 more source
Etanercept-Induced Anti-Glomerular Basement Membrane Disease
Anti-glomerular basement membrane (anti-GBM) disease is a rare form of small-vessel vasculitis that typically causes rapidly progressive glomerulonephritis with or without alveolar haemorrhage.
Saif Al-Chalabi +3 more
doaj +1 more source

