Results 21 to 30 of about 52,583 (282)

Molecular and Cellular Mechanisms Underlying the Initiation and Progression of Alport Glomerular Pathology

open access: yesFrontiers in Medicine, 2022
Alport syndrome results from a myriad of variants in the COL4A3, COL4A4, or COL4A5 genes that encode type IV (basement membrane) collagens. Unlike type IV collagen α1(IV)2α2(IV)1 heterotrimers, which are ubiquitous in basement membranes, α3/α4/α5 have a ...
Dominic Cosgrove, Jacob Madison
doaj   +1 more source

Anti-glomerular basement membrane disease [PDF]

open access: yesKidney International, 2003
Human anti-glomerular basement membrane (anti-GBM) disease is a rare disorder characterized by rapidly progressive glomerulonephritis (RPGN) and lung haemorrhage. However, it is the cause of only about one third of the cases of this clinical syndrome, and lung haemorrhage does not occur in all patients.
Pusey, CD   +13 more
openaire   +3 more sources

Tubular basement membrane deposits after allogeneic hematopoietic stem cell transplantation

open access: yesBMC Nephrology, 2023
Background Extraglomerular immune complex deposition is rare and only a few membranous nephropathy cases with tubular basement membrane deposits have been reported following allogeneic hematopoietic stem cell transplantation.
Wenyan Zhou   +4 more
doaj   +1 more source

Etanercept-Induced Anti-Glomerular Basement Membrane Disease

open access: yesCase Reports in Nephrology and Dialysis, 2021
Anti-glomerular basement membrane (anti-GBM) disease is a rare form of small-vessel vasculitis that typically causes rapidly progressive glomerulonephritis with or without alveolar haemorrhage.
Saif Al-Chalabi   +3 more
doaj   +1 more source

Anti-Glomerular Basement Membrane Disease [PDF]

open access: yesJournal of the American Society of Nephrology, 1999
Anti-glomerular basement membrane disease (anti-GBM) is a rare but well-characterized cause of glomerulonephritis. It is defined by the presence of autoantibodies directed at specific antigenic targets within the glomerular and/or pulmonary basement membrane.
D C, Kluth, A J, Rees
openaire   +2 more sources

Case Report of a Patient with Goodpasture’s Syndrome Who Relapsed While on Hemodialysis

open access: yesTurkish Journal of Nephrology, 2019
Goodpasture’s syndrome is a rare autoimmune disease in which anti-glomerular basement membrane antibodies damage the glomerular and alveolar basement membrane. Its relapse is very rare, compared to other pulmonary-renal syndromes.
Tuba Elif ŞENEL   +7 more
doaj   +1 more source

Permselectivity of the glomerular wall examined with iron compound tracer [PDF]

open access: yes, 1977
Rat kidney endothelial cell morphology was examined after introducing iron colloid particles of positive or negative charge to investigate the relationship between the electric charge and permeation through the glomerular capillary.
Hirata, Kooiti
core   +1 more source

Mechanisms of Podocyte Detachment, Podocyturia, and Risk of Progression of Glomerulopathies

open access: yesKidney Diseases, 2020
Background: Glomerulopathies are the main cause of ESRD. Primary or secondary causes of glomerular diseases comprise more than 70% of cases that end up in renal replacement therapies.
Hernán Trimarchi
doaj   +1 more source

Glomerular basement membrane and related glomerular disease [PDF]

open access: yesTranslational Research, 2012
The glomerular basement membrane (GBM) is lined by fenestrated endothelium from the capillary-lumen side and by interdigitating foot processes of the podocytes from the urinary- space side. These three layers of the glomerular capillary wall constitute the functional unit of the glomerular filtration barrier.
Ying Maggie, Chen, Jeffrey H, Miner
openaire   +2 more sources

Anti-glomerular basement membrane glomerulonephritis following nintedanib for idiopathic pulmonary fibrosis: a case report

open access: yesJournal of Medical Case Reports, 2017
Background We report a previously unrecognized and unreported case of a patient with anti-glomerular basement membrane glomerulonephritis following nintedanib, an orally active small molecule tyrosine kinase inhibitor.
Ibrahim Ismail   +3 more
doaj   +1 more source

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