Results 41 to 50 of about 52,583 (282)
Respiratory Medicine Case Reports, 2020 Anti-glomerular basement membrane disease (anti-GBM) is a well-documented, small vessel vasculitis that is classically associated with glomerulonephritis and alveolitis [1].
Jeremy Polman +3 more
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Thin glomerular basement membrane disease [PDF]
Kidney International, 2001 Isolated microscopic hematuria that begins in childhood and is of glomerular origin has a rather limited differential diagnosis, with Alport syndrome, IgA nephropathy, and benign familial hematuria as the most prevalent conditions. In a series of 322 children with persistent hematuria for longer than 6 months, biopsies were classified as IgA ...
openaire +2 more sources
Activation of Rac-1 and RhoA contributes to podocyte injury in chronic kidney disease [PDF]
, 2013 Rho-family GTPases like RhoA and Rac-1 are potent regulators of cellular signaling that control gene expression, migration and inflammation. Activation of Rho-GTPases has been linked to podocyte dysfunction, a feature of chronic kidney diseases (CKD). We
Amann, Kerstin +13 more
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Atypical anti-glomerular basement membrane disease [PDF]
Clinical Kidney Journal, 2015 Anti-glomerular basement membrane (anti-GBM) disease classically presents with aggressive necrotizing and crescentic glomerulonephritis, often with pulmonary hemorrhage. The pathologic hallmark is linear staining of GBMs for deposited immunoglobulin G (IgG), usually accompanied by serum autoantibodies to the collagen IV alpha-3 constituents of GBMs ...
Troxell, Megan L., Houghton, Donald C.
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Atypical Anti-Glomerular Basement Membrane Disease
Kidney International Reports, 2023 La maladie atypique de la membrane basale anti-glomérulaire (anti-GBM) est caractérisée par un dépôt d'immunoglobuline G (IgG) linéaire le long du GBM sans anticorps IgG anti-GBM circulants. Par rapport à la maladie anti-GBM classique, la maladie anti-GBM atypique a tendance à être plus douce avec une évolution plus indolente dans certains cas. De plus,
Joyita Bharati +3 more
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Urinary peptidomics analysis reveals proteases involved in diabetic nephropathy [PDF]
, 2017 Mechanisms underlying the onset and progression of nephropathy in diabetic patients are not fully elucidated. Deregulation of proteolytic systems is a known path leading to disease manifestation, therefore we hypothesized that proteases aberrantly ...
Bascands, Jean-Loup +15 more
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Myo1e impairment results in actin reorganization, podocyte dysfunction, and proteinuria in zebrafish and cultured podocytes. [PDF]
PLoS ONE, 2013 BackgroundPodocytes serve as an important constituent of the glomerular filtration barrier. Recently, we and others identified Myo1e as a key molecular component of the podocyte cytoskeleton.ResultsMyo1e mRNA and protein was expressed in human and mouse ...
Jianhua Mao +14 more
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Acta Clinica Croatica, 2021 Aim. To investigate morphological findings of zero-time biopsies analyzed at the Department of Nephropathology and Electron Microscopy, Dubrava University Hospital, Zagreb. Materials and methods.
Petar Šenjug +7 more
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TGF-beta 1-induced epithelial-to-mesenchymal transition and therapeutic intervention in diabetic nephropathy [PDF]
, 2010 Background/Aims: Epithelial-to-mesenchymal cell transformation (EMT) is the trans-differentiation of tubular epithelial cells into myofibroblasts, an event underlying progressive chronic kidney disease in diabetes, resulting in fibrosis.
Hills, Claire E., Squires, Paul E.
core +1 more source
Saudi Journal of Kidney Diseases and Transplantation, 2014 Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides is an important cause of rapidly progressive glomerulonephritides (RPGN), and they are classically described as pauci-immune diseases as evidenced by the absence of immune deposits on ...
Wiroon Sangsiraprapha +2 more
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