Results 1 to 10 of about 537,821 (190)

The Pathophysiological Role of Thymosin β4 in the Kidney Glomerulus [PDF]

open access: yesInternational Journal of Molecular Sciences, 2023
Diseases affecting the glomerulus, the filtration unit of the kidney, are a major cause of chronic kidney disease. Glomerular disease is characterised by injury of glomerular cells and is often accompanied by an inflammatory response that drives disease progression.
William John Mason   +1 more
exaly   +10 more sources

The integrin repertoire drives YAP-dependent epithelial:stromal interactions during injury of the kidney glomerulus [PDF]

open access: yesNature Communications
The kidney glomerulus is a filtration barrier in which capillary loop architecture depends on epithelial-stromal interactions between podocytes and mesangial cells.
Evelyne Huynh-Cong   +9 more
doaj   +2 more sources

Extracellular matrix and vascular dynamics in the kidney of a murine model for Marfan syndrome.

open access: yesPLoS ONE, 2023
Fibrillin-1 is a pivotal structural component of the kidney's glomerulus and peritubular tissue. Mutations in the fibrillin-1 gene result in Marfan syndrome (MFS), an autosomal dominant disease of the connective tissue.
Rodrigo Barbosa de Souza   +8 more
doaj   +1 more source

Alterations in Protein Translation and Carboxylic Acid Catabolic Processes in Diabetic Kidney Disease

open access: yesCells, 2022
Diabetic kidney disease (DKD) remains the leading cause of end-stage kidney disease despite decades of study. Alterations in the glomerulus and kidney tubules both contribute to the pathogenesis of DKD although the majority of investigative efforts have ...
Kimberly S. Collins   +14 more
doaj   +1 more source

Glycerol Improves Intracerebral Hemorrhagic Brain Injury and Associated Kidney Dysfunction in Rats

open access: yesAntioxidants, 2021
In stroke patients, the development of acute kidney injury (AKI) is closely linked with worse outcomes and increased mortality. In this study, the interplay between post-stroke and AKI and treatment options was investigated in a rodent model of ...
Cheng-Yi Chang   +7 more
doaj   +1 more source

Perconditioning combined with postconditioning on kidney ischemia and reperfusion [PDF]

open access: yesActa Cirúrgica Brasileira, 2017
Purpose: To evaluate if combination of perconditioning and postconditioning provides improved renal protection compared to perconditioning alone in a model of renal reperfusion injury.
Felipe Lobato da Silva Costa   +7 more
doaj   +2 more sources

Modelling Renal Filtration and Reabsorption Processes in a Human Glomerulus and Proximal Tubule Microphysiological System

open access: yesMicromachines, 2021
Kidney microphysiological systems (MPS) serve as potentially valuable preclinical instruments in probing mechanisms of renal clearance and osmoregulation. Current kidney MPS models target regions of the nephron, such as the glomerulus and proximal tubule
Stephanie Y. Zhang, Gretchen J. Mahler
doaj   +1 more source

MORPHOLOGICAL AND HISTOLOGICAL STUDY FOR THE KIDNEYS OF COOT BIRD ( Fulica atra ) [PDF]

open access: yesBasrah Journal of Veterinary Research, 2012
Present study were carried out on ten adult males of coot bird, for determinate the histological structure of kidneys. The results were showed that each kidney consisted of three parts, a large cranial (mean of its length 28±0.15mm and its width13±0.08mm)
Abbas Lafi Batah
doaj   +1 more source

Effect of Fluoxetine on Kidney of Albino Rats- A Histological Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2019
Introduction: Fluoxetine and other Selective Serotonin Reuptake Inhibitors (SSRIs) are reported to produce hyponatremia especially in elderly patients. Aim: To evaluate histological changes in kidney tissue of albino rats by different doses of fluoxetine
Alka Aggarwal   +3 more
doaj   +1 more source

Effect of Co-culture of mesenchymal stem cell and glomerulus endothelial cell to promote endothelialization under optimized perfusion flow rate in whole renal ECM scaffold

open access: yesMaterials Today Bio, 2022
In recent era, many researches on implantable bio-artificial organs has been increased owing to large gap between donors and receivers. Comprehensive organ based researches on perfusion culture for cell injury using different flow rate have not been ...
Minji Choi   +5 more
doaj   +1 more source

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