Results 41 to 50 of about 1,184,470 (278)

Kidney tubular injury of rats caused by unripe green betel nuts (Areca catechu)

JKKI (Jurnal Kedokteran dan Kesehatan Indonesia), 2020
Background: Unripe green betel nuts (Areca catechu) are usually consumed as herbal medicines by some inhabitants in several regions of Indonesia. It is considered that the nuts contain Arecoline hydrobromide that can cause damages in a kidney tubule ...
Ave Olivia Rahman, Anati Purwakanthi
doaj   +1 more source

Podocyte Endocytosis in Regulating the Glomerular Filtration Barrier

Frontiers in Medicine, 2022
Endocytosis is a mechanism that internalizes and recycles plasma membrane components and transmembrane receptors via vesicle formation, which is mediated by clathrin-dependent and clathrin-independent signaling pathways.
Xuefei Tian, Patricia Bunda, Shuta Ishibe   +2 more
doaj   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho, Karim M. Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I. Kamal, Balázs Szamosfalvi, Tibor Fülöp   +7 more
wiley   +1 more source

Non-Albumin Proteinuria (NAP) as a Complementary Marker for Diabetic Kidney Disease (DKD)

Life, 2021
Diabetic kidney disease (DKD) is one of the most common forms of chronic kidney disease. Its pathogenic mechanism is complex, and it can affect entire structures of the kidney.
Jaehyun Bae, Young Jun Won, Byung-Wan Lee   +2 more
doaj   +1 more source

In-depth proteomic profiling of the normal human kidney glomerulus using two-dimensional protein prefractionation in combination with liquid chromatography-tandem mass spectrometry.

Journal of Proteome Research, 2007
The kidney glomerulus plays a pivotal role in ultrafiltration of plasma into urine and also is the locus of kidney disease progressing to chronic renal failure.
Masahito Miyamoto, Y. Yoshida, Izumi Taguchi, Y. Nagasaka, M. Tasaki, Ying Zhang, Bo Xu, M. Nameta, H. Sezaki, L. M. Cuellar, Tetsuo Osawa, Hideo Morishita, Shigeki Sekiyama, Eishin Yaoita, K. Kimura, Tadashi Yamamoto   +15 more
semanticscholar   +1 more source

Somatostatin-like immunoreactivity in the glomerulus of rat kidney

Kidney International, 1983
It has been shown that somatostatin inhibits the antidiuretic action of vasopressin in toad urinary bladder in vitro and in dogs and rats in vivo. The presence of somatostatin-like immunoreactivity (SLI) in the urinary bladder and kidney of the toad has suggested the possibility that somatostatin may act as a local paracrine hormone modulating the ...
Kurokawa, Kiyoshi, Aponte, Gregory W., Fujibayashi, Shigeru, Yamada, Tadataka   +3 more
openaire   +2 more sources

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Myocilin is expressed in the glomerulus of the kidney and induced in mesangioproliferative glomerulonephritis [PDF]

Kidney International, 2005
Myocilin is a 55 to 57 kD secreted glycoprotein and member of the olfactomedin protein family. It is expressed in high amounts in the outflow tissues of the aqueous humor in the eye where it is supposed to contribute to outflow resistance. Myocilin is mutated in some forms of primary open angle glaucoma and affected patients show very high intraocular ...
Goldwich, Andreas, Baulmann, Daniela C., Ohlmann, Andreas, Fluugel-Koch, Cassandra, Schocklmann, Harald, Tamm, Ernst R.   +5 more
openaire   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source