Results 1 to 10 of about 152,808 (261)
To form and function: on the role of basement membrane mechanics in tissue development, homeostasis and disease [PDF]
Open Biology, 2021 The basement membrane (BM) is a special type of extracellular matrix that lines the basal side of epithelial and endothelial tissues. Functionally, the BM is important for providing physical and biochemical cues to the overlying cells, sculpting the ...
Nargess Khalilgharibi, Yanlan Mao
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Basement membrane perforations guide anterior–posterior axis formation [PDF]
Nature CommunicationsEstablishment of the anterior-posterior (AP) axis is a critical symmetry-breaking event in mammalian development. In mice, this process involves the directed migration of the distal visceral endoderm (DVE).
Dong-Yuan Chen +9 more
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Vascular Basement Membrane Fragmentation in Keloids and the Expression of Key Basement Membrane Component Genes [PDF]
Plastic and Reconstructive Surgery, Global OpenBackground:. Keloids are growing scars that arise from injury to the reticular dermis and subsequent chronic local inflammation. The latter may be promoted by vascular hyperpermeability, which permits the ingress of chronic inflammatory cells/factors ...
Yusaku Saijo, MD +3 more
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Anti-GBM disease with positive serum anti-GBM antibodies but negative IgG deposition: A case report
SAGE Open Medical Case Reports, 2023 Anti-glomerular basement membrane antibodies are significantly specific for detecting anti-glomerular basement membrane disease. These antibodies are typically targeted against the non-collagenous (NC1) domain of the alpha 3 chain of type IV collagen and,
Kimia Kazemzadeh +3 more
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Long Prehensile Protrusions Can Facilitate Cancer Cell Invasion through the Basement Membrane
Cells, 2023 A basic process in cancer is the breaching of basement-membrane barriers to permit tissue invasion. Cancer cells can use proteases and physical mechanisms to produce initial holes in basement membranes, but how cells squeeze through this barrier into ...
Shayan S. Nazari +3 more
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Mechanisms of Basement Membrane Micro-Perforation during Cancer Cell Invasion into a 3D Collagen Gel
Gels, 2022 Cancer invasion through basement membranes represents the initial step of tumor dissemination and metastasis. However, little is known about how human cancer cells breach basement membranes.
Shayan S. Nazari +2 more
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The prognostic significance of type IV collagen expression in colorectal carcinomas [PDF]
Archive of Oncology, 2003 BACKGROUND: Breakdown of basement membrane is believed to be an essential step for tumor invasion and metastasis. The interaction between tumor cells and extracellular matrix can also result in induction of basement membrane synthesis by tumor and ...
Fenyvesi Attila
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Current Biology, 2017 Basement membranes (BMs) are thin, dense sheets of specialized, self-assembled extracellular matrix that surround most animal tissues (Figure 1, top). The emergence of BMs coincided with the origin of multicellularity in animals, suggesting that they were essential for the formation of tissues.
Ranjay, Jayadev, David R, Sherwood
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Basement membrane components [PDF]
Journal of Clinical Pathology, 2003 New blood tests in inflammatory bowel disease Idiopathic inflammatory bowel disease (IBD) collectively describes ulcerative colitis (UC) and Crohn’s disease (CD). UC is characterised by inflammation limited to the colonic mucosa and collagen deposition only in the submucosa,1 whereas CD is characterised by transmural, granulomatous inflammation and ...
A C Y, Li, R P H, Thompson
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Stem Cells Translational Medicine, 2021 The differentiation of human stem cells into insulin secreting beta‐like cells holds great promise to treat diabetes. Current protocols drive stem cells through stages of directed differentiation and maturation and produce cells that secrete insulin in ...
Reena Singh +7 more
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