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To form and function: on the role of basement membrane mechanics in tissue development, homeostasis and disease [PDF]
Open Biology, 2021 The basement membrane (BM) is a special type of extracellular matrix that lines the basal side of epithelial and endothelial tissues. Functionally, the BM is important for providing physical and biochemical cues to the overlying cells, sculpting the ...
Nargess Khalilgharibi, Yanlan Mao
doaj +3 more sources
Beyond proteases: Basement membrane mechanics and cancer invasion
Journal of Cell Biology, 2019 Chang and Chaudhuri discuss basement membrane mechanics and how cells use both proteolytic and physical mechanisms to invade basement membranes during cancer progression.
Julie Chang +2 more
exaly +2 more sources
The vascular basement membrane in the healthy and pathological brain
Journal of Cerebral Blood Flow and Metabolism, 2017 The vascular basement membrane contributes to the integrity of the blood-brain barrier (BBB), which is formed by brain capillary endothelial cells (BCECs).
Torben Moos
exaly +2 more sources
Case Report: Elderly anti-GBM antibody disease with diffuse non-hereditary glomerular basement membrane thinning of uncertain etiology [PDF]
Frontiers in MedicineAnti-glomerular basement membrane (GBM) antibody disease is an autoimmune-mediated rapidly progressive renal injury. The coexistence of diffuse non-hereditary glomerular basement membrane thinning of uncertain etiology in elderly patients is clinically ...
Pei Yu +8 more
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Traversing the basement membrane in vivo: A diversity of strategies
Journal of Cell Biology, 2014 The basement membrane is a dense, highly cross-linked, sheet-like extracellular matrix that underlies all epithelia and endothelia in multicellular animals.
David R Sherwood +2 more
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Developmental Biology, 2014 Many epithelial tissues expand rapidly during embryonic development while remaining surrounded by a basement membrane. Remodeling of the basement membrane is assumed to occur during branching morphogenesis to accommodate epithelial growth, but how such ...
Kenneth Yamada
exaly +2 more sources
Basement membrane perforations guide anterior–posterior axis formation [PDF]
Nature CommunicationsEstablishment of the anterior-posterior (AP) axis is a critical symmetry-breaking event in mammalian development. In mice, this process involves the directed migration of the distal visceral endoderm (DVE).
Dong-Yuan Chen +9 more
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Signal Transduction and Targeted Therapy, 2021 SARS-CoV-2 has been reported to show a capacity for invading the brains of humans and model animals. However, it remains unclear whether and how SARS-CoV-2 crosses the blood–brain barrier (BBB).
Ling Zhang +20 more
semanticscholar +1 more source
Basement membrane stiffness determines metastases formation
Nature Materials, 2021 The basement membrane (BM) is a special type of extracellular matrix and presents the major barrier cancer cells have to overcome multiple times to form metastases.
R. Reuten +30 more
semanticscholar +1 more source
Anti-GBM disease with positive serum anti-GBM antibodies but negative IgG deposition: A case report
SAGE Open Medical Case Reports, 2023 Anti-glomerular basement membrane antibodies are significantly specific for detecting anti-glomerular basement membrane disease. These antibodies are typically targeted against the non-collagenous (NC1) domain of the alpha 3 chain of type IV collagen and,
Kimia Kazemzadeh +3 more
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