Results 41 to 50 of about 257,213 (299)

Permselectivity of the glomerular wall examined with iron compound tracer [PDF]

, 1977
Rat kidney endothelial cell morphology was examined after introducing iron colloid particles of positive or negative charge to investigate the relationship between the electric charge and permeation through the glomerular capillary.
Hirata, Kooiti
core   +1 more source

Ultrastructure of neurovascular changes in human diabetic retinopathy [PDF]

, 2018
The previous concept regarding diabetic retinopathy assigned a primary role to hyperglycemia-induced microvascular alterations, while neuronal and glial abnormalities were considered to be secondary to either ischemia or exudation.
Artico, Marco, Biró, Zsolt, Fehér, János, Micera, Alessandra, Orlando, Maria Patrizia, Scuderi, Gianluca, Spoletini, Maria Luisa, Taurone, Samanta, Turchetta, Rosaria, Varsányi, Balázs   +9 more
core   +1 more source

Ccl2 and Ccl3 Mediate Neutrophil Recruitment via Induction of Protein Synthesis and Generation of Lipid Mediators [PDF]

, 2009
Objective: Although the chemokines monocyte chemoattractant protein-1 (Ccl2/JE/MCP-1) and macrophage inflammatory protein-1α (Ccl3/MIP-1α) have recently been implicated in neutrophil migration, the underlying mechanisms remain largely unclear.
Berberich, Nina, Bihari, Peter, Khandoga, Alexander G., Krombach, Fritz, Lerchenberger, Max, Rehberg, Markus, Reichel, Christoph A., Zahler, Stefan   +7 more
core   +1 more source

Molecular and Cellular Mechanisms Underlying the Initiation and Progression of Alport Glomerular Pathology

Frontiers in Medicine, 2022
Alport syndrome results from a myriad of variants in the COL4A3, COL4A4, or COL4A5 genes that encode type IV (basement membrane) collagens. Unlike type IV collagen α1(IV)2α2(IV)1 heterotrimers, which are ubiquitous in basement membranes, α3/α4/α5 have a ...
Dominic Cosgrove, Jacob Madison
doaj   +1 more source

Anti-glomerular basement membrane glomerulonephritis following nintedanib for idiopathic pulmonary fibrosis: a case report

Journal of Medical Case Reports, 2017
Background We report a previously unrecognized and unreported case of a patient with anti-glomerular basement membrane glomerulonephritis following nintedanib, an orally active small molecule tyrosine kinase inhibitor.
Ibrahim Ismail, Sonu Nigam, Alan Parnham, Vinay Srinivasa   +3 more
doaj   +1 more source

Phagocytic properties of lung alveolar wall cells [PDF]

, 1974
For the purpose to define the mechanism of heavy metal intoxication by inhalation, morphologic observations were made on rat lungs after nasal instillation of iron colloid particles of positive and negative electric charges. Histochemical observation was
Tanaka, Akisuke
core   +1 more source

Mapping the molecular and structural specialization of the skin basement membrane for inter-tissue interactions

Nature Communications, 2021
The basement membrane is located at tissue interfaces, but how it mediates distinct inter-tissue interactions is unclear. Here, the authors systematically define the spatial heterogeneity of skin basement membrane composition and show its functional ...
Ko Tsutsui, Hiroki Machida, Asako Nakagawa, Kyungmin Ahn, Ritsuko Morita, Kiyotoshi Sekiguchi, Jeffrey H. Miner, Hironobu Fujiwara   +7 more
doaj   +1 more source

Adhesive and degradative properties of human placental cytotrophoblast cells in vitro. [PDF]

, 1989
Human fetal development depends on the embryo rapidly gaining access to the maternal circulation. The trophoblast cells that form the fetal portion of the human placenta have solved this problem by transiently exhibiting certain tumor-like properties ...
Cui, TY, Damsky, CH, Fisher, SJ, Grahl, K, Hartman, L, Tarpey, J, Zhang, GY, Zhang, L   +7 more
core   +3 more sources

ER stress and basement membrane defects combine to cause glomerular and tubular renal disease resulting from Col4a1 mutations in mice

Disease Models & Mechanisms, 2016
Collagen IV is a major component of basement membranes, and mutations in COL4A1, which encodes collagen IV alpha chain 1, cause a multisystemic disease encompassing cerebrovascular, eye and kidney defects.
Frances E. Jones, Matthew A. Bailey, Lydia S. Murray, Yinhui Lu, Sarah McNeilly, Ursula Schlötzer-Schrehardt, Rachel Lennon, Yoshikazu Sado, David G. Brownstein, John J. Mullins, Karl E. Kadler, Tom Van Agtmael   +11 more
doaj   +1 more source

Clinical Significance of Zero-Time Renal Transplant Biopsies and Thin Glomerular Basement Membranes in Zero-Time Renal Transplant Biopsies

Acta Clinica Croatica, 2021
Aim. To investigate morphological findings of zero-time biopsies analyzed at the Department of Nephropathology and Electron Microscopy, Dubrava University Hospital, Zagreb. Materials and methods.
Petar Šenjug, Matija Horaček, Bojana Maksimović, Ksenija Vučur, Ivica Horvatić, Nikola Zagorec, Mladen Knotek, Danica Galešić Ljubanović   +7 more
doaj   +1 more source